Protein Alignment Rab35 and RAB3A

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 89/196 - (45%)
• Similarity: 131/196 - (66%)
• Gaps: 9/196 - (4%)

  Fly     3 RGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQ 67
            :.||::||:||||:|.|||:|.|.|::||:|:.::::|:|:|||::|:.....|:||||||||||
Human    17 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQ 81

  Fly    68 ERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQN-NCDVVKKVLVGNKNDDPDRKVVI 131
            ||:||||:.||||..|.|::||:||.|||..|:.|..:|:. :.|..:.:|||||.|..|.:||.
Human    82 ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVS 146

  Fly   132 TEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKPNPKGSKG 196
            :|..::.|..:..|.||.||||||||:..|..:. .|:..|:     .:..||  ..|...|:|.
Human   147 SERGRQLADHLGFEFFEASAKDNINVKQTFERLV-DVICEKM-----SESLDT--ADPAVTGAKQ 203

  Fly   197 G 197
            |
Human   204 G 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	89/196 (45%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	80/164 (49%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		2/8 (25%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		12/15 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		4/11 (36%)