Protein Alignment Rab35 and RAB40C

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_066991.3
• Gene: RAB40C / 57799
• HGNCID: 18285
• Length: 281
• Species: Homo sapiens
• Alignment Length: 200
• Identity: 73/200 - (36%)
• Similarity: 111/200 - (55%)
• Gaps: 11/200 - (5%)

  Fly     3 RGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQ 67
            :.:|:|.|.|::|||.|||..:|....|......|..:.|:|:|..|:.::|.||||::|||:||
Human     9 KSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNGIDYKTTTILLDGRRVKLELWDTSGQ 73

  Fly    68 ERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDVVKKVLVGNKNDDPDRKVVIT 132
            .||.||..:|.||..|:::|||:||..||..:.||::||..:...|.::||||:.....::.|.|
Human    74 GRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPGVPRILVGNRLHLAFKRQVPT 138

  Fly   133 EDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVL-DHKLRTSPNEQQKDTLHLKPNPKGSKG 196
            |.|:.:|::..:..||.|...|.||...|..::|.|| .|.:...          .:||...|..
Human   139 EQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMRHGMEKI----------WRPNRVFSLQ 193

  Fly   197 GKCCR 201
            ..|||
Human   194 DLCCR 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	71/198 (36%)
RAB40C	NP_066991.3	Rab40	9..281	CDD:133321	72/199 (36%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		1/7 (14%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		9/15 (60%)
		SOCS_Rab40	187..229	CDD:239711	4/11 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..281