DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab35 and rab13

DIOPT Version :9

Sequence 1:	NP_001188678.1	Gene:	Rab35 / 33014	FlyBaseID:	FBgn0031090	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_958486.1	Gene:	rab13 / 373105	ZFINID:	ZDB-GENE-030826-30	Length:	200	Species:	Danio rerio

Alignment Length:	194	Identity:	94/194 - (48%)
Similarity:	139/194 - (71%)	Gaps:	14/194 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MARGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTA 65
            ||:.:|.|||||:||||||||:.|:|||::|.|:.:||:|||:|||::|:::||.:||||:||||
Zfish     1 MAKKYDFLFKLLLIGDSGVGKTCLIIRFAEDNFNSTYISTIGIDFKVKTIEVEGKKVKLQVWDTA 65

  Fly    66 GQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDV-VKKVLVGNKNDDPDRKV 129
            |||||:|||:.||||..|:|:|||:|:.:|:.|::.|::.|:.|... |.::|:|||.|...::.
Zfish    66 GQERFKTITTAYYRGAMGIILVYDITDEKSYENIQNWMKSIKENASAGVSRMLLGNKCDIEAKRK 130

  Fly   130 VITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKPNPKG 193
            |..|..::.||:..|..||||||.:||||..|.|:.|.:|   |:::.          ||.|.|
Zfish   131 VSKETGEKLAKEHGIRFFETSAKSSINVEESFTSLARDIL---LKSNK----------KPGPSG 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_001188678.1	Rab35	3..201	CDD:133310	92/192 (48%)
rab13	NP_958486.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	87/168 (52%)
		RAB	9..170	CDD:197555	84/160 (53%)
		Effector region. /evidence=ECO:0000250	37..45		5/7 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..195		4/19 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910