Protein Alignment Rab35 and RAB21

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_055814.1
• Gene: RAB21 / 23011
• HGNCID: 18263
• Length: 225
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 68/210 - (32%)
• Similarity: 125/210 - (59%)
• Gaps: 11/210 - (5%)

  Fly     2 ARGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAG 66
            |.|..:.||::::|:..|||:||::|:.::.|:..:|||:...|..:.::|.|.||.|.||||||
Human    13 AAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG 77

  Fly    67 QERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNC-DVVKKVLVGNKNDDPDRKVV 130
            ||||..:...|||.::|.|:|||:|:.:||..|:.|::|::... :.:...:||||.|....:.|
Human    78 QERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHV 142

  Fly   131 ITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVL-----DHKLR----TSPNEQQKDTLH 186
            ..::|:.:|:.:..:.:.||||.|..:|.:||.:.::::     |.:.:    :.|...::....
Human   143 SIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGTARRGVQI 207

  Fly   187 LKPNPKG-SKGGKCC 200
            :...|:. :.||.||
Human   208 IDDEPQAQTSGGGCC 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	67/209 (32%)
RAB21	NP_055814.1	Rab21	20..181	CDD:133323	59/160 (37%)