Protein Alignment Rab35 and RAB12

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_001020471.3
• Gene: RAB12 / 201475
• HGNCID: 31332
• Length: 340
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 85/198 - (42%)
• Similarity: 130/198 - (65%)
• Gaps: 13/198 - (6%)

  Fly     3 RGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQ 67
            |..|...:::|||..||||:||:.||:||||..:..:|:||||||:||::.|.:::|||||||||
Human   133 RPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQ 197

  Fly    68 ERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNC-DVVKKVLVGNKND-DPDRKVV 130
            |||.:|||.|||...|:|:|||:|..|:|.::.:|::.|.... :..:.:|||||.| :.||::.
Human   198 ERFNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLDCETDREIT 262

  Fly   131 ITEDAQRFAKQM-DIELFETSAKDNINVENMFLSITRQVLDHKLRTSP-----NEQQKDTLHLKP 189
             .:..::||:|: .:...|.|||||.||:.:||    :::|..|:..|     ||.....|.|:|
Human   263 -RQQGEKFAQQITGMRFCEASAKDNFNVDEIFL----KLVDDILKKMPLDILRNELSNSILSLQP 322

  Fly   190 NPK 192
            .|:
Human   323 EPE 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	85/198 (43%)
RAB12	NP_001020471.3	Rab12	139..340	CDD:206699	83/192 (43%)