Protein Alignment Rab35 and Rab4a

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_033029.2
• Gene: Rab4a / 19341
• MGIID: 105069
• Length: 218
• Species: Mus musculus
• Alignment Length: 200
• Identity: 81/200 - (40%)
• Similarity: 117/200 - (58%)
• Gaps: 21/200 - (10%)

  Fly     1 MARGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTA 65
            |:..:|.|||.|:||::|.|||.||.:|.:..|......||||:|..:.:::.|..|||||||||
Mouse     6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTA 70

  Fly    66 GQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEI-----QNNCDVVKKVLVGNKND-D 124
            ||||||::|.:||||..|.::|||:|:.|::..:..||.:.     ||    :..:|.|||.| |
Mouse    71 GQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQN----IVLILCGNKKDLD 131

  Fly   125 PDRKVVITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKP 189
            .||:|...| |.|||::.::...||||....|||..|:...|::| :|:.:.         .|.|
Mouse   132 ADREVTFLE-ASRFAQENELMFLETSALTGENVEEAFMQCARKIL-NKIESG---------ELDP 185

  Fly   190 NPKGS 194
            ...||
Mouse   186 ERMGS 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	79/197 (40%)
Rab4a	NP_033029.2	Rab4	14..174	CDD:206696	72/164 (44%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	44..49		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	70..79		7/8 (88%)