DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab35 and rab-1

DIOPT Version :9

Sequence 1:	NP_001188678.1	Gene:	Rab35 / 33014	FlyBaseID:	FBgn0031090	Length:	201	Species:	Drosophila melanogaster
Sequence 2:	NP_503397.1	Gene:	rab-1 / 178620	WormBaseID:	WBGene00004266	Length:	205	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	108/201 - (53%)
Similarity:	145/201 - (72%)	Gaps:	8/201 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQER 69
            :|:|||||:|||||||||.||:||:|||::.|||:||||||||||::::|..:||||||||||||
Worm     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72

  Fly    70 FRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQN-NCDVVKKVLVGNKNDDPDRKVVITE 133
            ||||||:||||.||:|||||:|:.|:|.||::||:||.. .|:.|.|:|||||.|...::.|.|:
Worm    73 FRTITSSYYRGAHGIIVVYDITDQETFNNVKQWLQEIDRYACENVNKLLVGNKCDLTAKRAVETQ 137

  Fly   134 DAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLK---PNP-KGS 194
            .||.:|.|:.|...|||||.:.|||..||::..::   |.|..|.:.......::   ..| :..
Worm   138 AAQDYAGQLGIPFLETSAKSSTNVEQAFLTMASEI---KSRMGPVQGAGGAPGVRITGSQPVQDK 199

  Fly   195 KGGKCC 200
            |.|.||
Worm   200 KSGGCC 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_001188678.1	Rab35	3..201	CDD:133310	108/201 (54%)
rab-1	NP_503397.1	Rab1_Ypt1	10..175	CDD:206661	100/167 (60%)
rab-1	NP_503397.1	RAB	12..175	CDD:197555	99/165 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1149105at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920