Protein Alignment Rab35 and RAB31

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_006859.2
• Gene: RAB31 / 11031
• HGNCID: 9771
• Length: 195
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 73/196 - (37%)
• Similarity: 117/196 - (59%)
• Gaps: 13/196 - (6%)

  Fly    10 KLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQERFRTIT 74
            |:.::||:||||||::.||..|.|..:...|||..|..:||.......|..||||||||||.::.
Human     8 KVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLA 72

  Fly    75 STYYRGTHGVIVVYDVTNGESFANVRRWLEEI-QNNCDVVKKVLVGNKNDDPDRKVVITEDAQRF 138
            ..||||:...::|||:|..:||..:::|::|: ::..:.:...:.|||.|..|.:.|..:||:.:
Human    73 PMYYRGSAAAVIVYDITKQDSFYTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEY 137

  Fly   139 AKQMDIELFETSAKDNINVENMFLSITRQV--LDHKLRTSPNEQ-QKDTLHL-KPNPKGSKGGKC 199
            |:.:...:.|||||:.||:|.:|..|:||:  ||      |:|. ...|:.: ||..:.|:  :|
Human   138 AESIGAIVVETSAKNAINIEELFQGISRQIPPLD------PHENGNNGTIKVEKPTMQASR--RC 194

  Fly   200 C 200
            |
Human   195 C 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	73/196 (37%)
RAB31	NP_006859.2	Rab5_related	6..168	CDD:206653	63/159 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	30..42		4/11 (36%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	63..79		9/15 (60%)