DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rab35 and IFT27

DIOPT Version :9

Sequence 1:NP_001188678.1 Gene:Rab35 / 33014 FlyBaseID:FBgn0031090 Length:201 Species:Drosophila melanogaster
Sequence 2:NP_001171172.1 Gene:IFT27 / 11020 HGNCID:18626 Length:186 Species:Homo sapiens


Alignment Length:170 Identity:62/170 - (36%)
Similarity:94/170 - (55%) Gaps:8/170 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 KLLIIGDSGVGKSSLLIRFSDD--TFSGSYITTIGVDFKIRTVDI--EGMRVKLQIWDTAGQERF 70
            |.::.||..|||::|...|..|  .|..||..|.|:|..::||.:  .|..|:|.|:|:||:|.|
Human     7 KCILAGDPAVGKTALAQIFRSDGAHFQKSYTLTTGMDLVVKTVPVPDTGDSVELFIFDSAGKELF 71

  Fly    71 RTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDVVK--KVLVGNKNDDPDRKVVITE 133
            ..:....:...:.:.:||||||.|||.|..:|||:.::....:.  .||||||.|...|:.|.:.
Human    72 SEMLDKLWESPNVLCLVYDVTNEESFNNCSKWLEKARSQAPGISLPGVLVGNKTDLAGRRAVDSA 136

  Fly   134 DAQRFAKQMDIELFETSAKDNINVENMFLSITRQVLDHKL 173
            :|:.:|....:|.||||.|:..|.|..|..:.:|.  |:|
Human   137 EARAWALGQGLECFETSVKEMENFEAPFHCLAKQF--HQL 174

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab35NP_001188678.1 Rab35 3..201 CDD:133310 62/170 (36%)
IFT27NP_001171172.1 RabL4 6..172 CDD:206688 60/166 (36%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0079
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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