DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and FKH2

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_014331.3	Gene:	FKH2 / 855656	SGDID:	S000005012	Length:	862	Species:	Saccharomyces cerevisiae

Alignment Length:	237	Identity:	68/237 - (28%)
Similarity:	108/237 - (45%)	Gaps:	46/237 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 ISKHNSGSSFSSCSSSSSNSSSDSMAAKSNAKPAFTYSALIVMAIWSSSEKRLTLSGICKWIADN 91
            :..:.|.:::......:|:.|.|.   ..|.||..:|:.:|..||.||.|..::|:.|.|:|:.|
Yeast   312 VDSYKSSNAYPQALDFTSDLSHDE---NRNVKPPHSYATMITQAILSSPEGVISLADIYKYISSN 373

  Fly    92 FPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWAL-DPYAEDLSIGETTGRLRRSNW 155
            :.|||..||.||||||||||||..|.:|||..::||:|..|.: :.|.::.          .:.|
Yeast   374 YAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKGMKWRISESYQQEF----------LNKW 428

  Fly   156 QQNTGARPKVTGHPYQRMPYYGHGHGNGPYIKAHSAYF---PI-MDHQHHAAMVQHYQAMMHRYQ 216
              |||...|:.           .|......::.|.|.|   |: ||::....|.|..:..:..:.
Yeast   429 --NTGKVGKIR-----------RGSSVARQLQLHMAKFNSLPMEMDYRLSLNMAQPPKRQLQSHN 480

  Fly   217 MMPHPHHH------QH---------QHQHQHPHSHFIQQSKP 243
            ::...:::      ||         ..|.|.|.||..|..:|
Yeast   481 VLEPSNNNIIEGFVQHVPSKGNLPASQQSQPPVSHQNQSQQP 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	39/77 (51%)
FKH2	NP_014331.3	COG5025	1..610	CDD:227358	68/237 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	97	1.000	Domainoid score	I1615
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	1	1.000	-	-		otm46522
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810