DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and foxk2b

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	XP_001922856.1	Gene:	foxk2b / 798356	ZFINID:	ZDB-GENE-030131-5310	Length:	597	Species:	Danio rerio

Alignment Length:	246	Identity:	72/246 - (29%)
Similarity:	115/246 - (46%)	Gaps:	51/246 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SVDKKEESPISKHNSGSS------------FSSCSSSSSN--SSSDSMAAKSNAKPAFTYSALIV 68
            ::......|.|...:|||            ..:.:|.|.|  .:|:..:.|.::||.::|:.|||
Zfish   157 TISAANSCPSSPRGAGSSGYRLGRIVPDLQLMNDNSQSENDKETSEGDSPKDDSKPPYSYAQLIV 221

  Fly    69 MAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWA 133
            .||..:.:|:|||:||...|..|:|||||....||||||||||||.:|::|||:.::||:|.:|.
Zfish   222 QAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWR 286

  Fly   134 LDPYAEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGPYIKAHSAYFPIMDH 198
            :||.:|        |:|....:::.   ||:  |.|..|.|.......:.|....||...
Zfish   287 IDPSSE--------GKLVEQAFRKR---RPR--GVPCFRTPLGPLSSRSAPASPNHSGVL----- 333

  Fly   199 QHHAAMVQHYQAMMHRYQMMPHPHHHQHQHQHQHPHSHFIQQSKPLHIQEP 249
            ..|::.||...::......:|                   .:|:|:.:..|
Zfish   334 SAHSSGVQTPDSLSREGSPVP-------------------MESEPVSVPPP 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	41/76 (54%)
foxk2b	XP_001922856.1	FHA	17..109	CDD:238017
foxk2b	XP_001922856.1	Forkhead	211..297	CDD:278670	46/93 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820