DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd19B and FOXB2

DIOPT Version :9

Sequence 1:NP_608369.1 Gene:fd19B / 33010 FlyBaseID:FBgn0031086 Length:260 Species:Drosophila melanogaster
Sequence 2:NP_001013757.1 Gene:FOXB2 / 442425 HGNCID:23315 Length:432 Species:Homo sapiens


Alignment Length:210 Identity:76/210 - (36%)
Similarity:95/210 - (45%) Gaps:39/210 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    55 SNAKPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRV 119
            |:.||.::|.:|..|||..|:||.|.||.|.|:|.:.|||||.....||||:|||||.|..|:::
Human    10 SDQKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKI 74

  Fly   120 PRALDDPGRGHYWALDPYAEDLSIGETTGRLRRSNWQQNTGARPKVT----GHPYQRMPYYGHGH 180
            ||..|.||:|.:|||.|...|:.  |....|||..       |.||.    .|.:........|.
Human    75 PRRPDQPGKGSFWALHPDCGDMF--ENGSFLRRRK-------RFKVLRADHTHLHAGSTKSAPGA 130

  Fly   181 GNGPYIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHPHHHQHQHQHQ--------HPHS-H 236
            |.|.::..|..:.|...|.||||                 .|||.|.|..|        .||. |
Human   131 GPGGHLHPHHHHHPHHHHHHHAA-----------------AHHHHHHHPPQPPPPPPPPPPHMVH 178

  Fly   237 FIQQSKPLHIQEPYH 251
            :..|..|...|.|.|
Human   179 YFHQQPPTAPQPPPH 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd19BNP_608369.1 FH 58..135 CDD:238016 40/76 (53%)
FOXB2NP_001013757.1 FH 13..101 CDD:214627 44/89 (49%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..220 25/93 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 413..432
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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