DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and foxg1b

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_998079.2	Gene:	foxg1b / 405850	ZFINID:	ZDB-GENE-040426-2437	Length:	341	Species:	Danio rerio

Alignment Length:	231	Identity:	92/231 - (39%)
Similarity:	123/231 - (53%)	Gaps:	29/231 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SSFSIRSLL------SVDKKEE---SP-----ISKHNSGSSFSSCSSSSSNSSSDSMAAKSNAKP 59
            :||||:|||      |.|:..|   ||     :.|....:...:....:......:...|...||
Zfish    14 TSFSIKSLLLPSKFDSADESAERGGSPAPVQDLDKPPEDAEMDNAQRDAEEPELQTKKGKKFDKP 78

  Fly    60 AFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALD 124
            .|:|:|||:|||..|.||||||:||.::|..||||||..|..||||||||||||..||:|||..|
Zfish    79 PFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYREHKQGWQNSIRHNLSLNKCFVKVPRHYD 143

  Fly   125 DPGRGHYWALDPYAEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGPYIKAH 189
            |||:|:||.|||.::|:.||.|||:|||    ::..:|.|:......|....|.|.|..|....:
Zfish   144 DPGKGNYWMLDPSSDDVFIGGTTGKLRR----RSATSRGKLVMKRGLRFAPLGLGLGERPSNPLY 204

  Fly   190 ---SAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHPH 222
               |.:.|:    ||:    ||....|.:....|.:
Zfish   205 WQLSPFLPL----HHS----HYNGSAHGFLNQGHTY 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	51/76 (67%)
foxg1b	NP_998079.2	FH	77..165	CDD:214627	57/87 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596116
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1751
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.750