DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fd19B and foxa2

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_989423.1	Gene:	foxa2 / 395063	XenbaseID:	XB-GENE-480476	Length:	434	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	87/307 - (28%)
Similarity:	129/307 - (42%)	Gaps:	72/307 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TPIFQSSFSIRSLLSVDKKEESPISKHNSGSSFSSCSSSSSNSSSDSMAAK---SNAKPAFTYSA 65
            :|:...:.|:.:|        :|.:..||.|..  ...|:.|.|.|....:   ::|||.::|.:
Frog   102 SPMSAQATSMNAL--------APYTNMNSMSPI--YGQSNINRSRDPKTYRRSYTHAKPPYSYIS 156

  Fly    66 LIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGH 130
            ||.|||..|..|.||||.|.:||.|.||:||..:..|||||||:||.|..|::|||:.|.||:|.
Frog   157 LITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGS 221

  Fly   131 YWALDPYA-----------------------------EDLSIGETT-GRLRRSNWQQNTG-ARPK 164
            :|.|.|.:                             :.||.|.:: |....|:.:.:.| ..|.
Frog   222 FWTLHPDSGNMFENGCYLRRQKRFKCEKKPSLREGGGKKLSEGSSSVGSAANSSSESSVGNESPH 286

  Fly   165 VTGHPYQR----MPYYGHGHGNGPYIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHPHHH- 224
            .:..|.|.    :.......|..|   .|:| .|....||  .:.||:..:.|..|....|.||
Frog   287 SSSSPCQEQKRSLVDMKSSQGLSP---DHAA-SPASQAQH--LLSQHHSVLSHEAQSHLKPEHHY 345

  Fly   225 ----------------QHQHQHQHPHSHFIQQSKPLHIQEPYHHTRY 255
                            ||.|.|.|.|.|..:.....: ::..|::.|
Frog   346 SFNHPFSINNLMSSEQQHHHHHHHNHHHHHKMDLKAY-EQVMHYSGY 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	41/76 (54%)
foxa2	NP_989423.1	Forkhead_N	17..148	CDD:369872	11/55 (20%)
		FH	149..237	CDD:214627	43/87 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	249..339		20/95 (21%)
		HNF_C	349..423	CDD:370449	9/44 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910