DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and foxi4.2

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_989265.1	Gene:	foxi4.2 / 394878	XenbaseID:	XB-GENE-487658	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	197	Identity:	67/197 - (34%)
Similarity:	96/197 - (48%)	Gaps:	32/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PIFQSSFSIRSLLSVDKKEESPISKHNSGSSFSSCSSSSSNSSSDSMAAKSNAKPAFTYSALIVM 69
            |....||      ...:::..|.|....|:..|..|::|...      .....:|.::|||||.|
Frog    84 PYMPPSF------GAPQRQFLPNSPAFGGTELSWMSAASQEE------LLKMVRPPYSYSALIAM 136

  Fly    70 AIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWAL 134
            ||..:|::|||||.|.:::|:|||:|:..|:.||||||||||||..|.:|||..:|||:|:||.|
Frog   137 AIQHASDRRLTLSQIYQYVAENFPFYKKSKAGWQNSIRHNLSLNDCFKKVPRDENDPGKGNYWTL 201

  Fly   135 DPYAEDLSIGETTGRLRRSNWQQNTG----------------ARPKVT-GHPYQRMPYYGHGHGN 182
            ||..|.:.......|.|:.....|:.                :.|.:| ..|.:..|   .||..
Frog   202 DPNCEKMFDNGNFRRKRKPKSDANSAKIAKIGEDHLNPKGKESPPMITPSSPEEPSP---TGHSK 263

  Fly   183 GP 184
            .|
Frog   264 SP 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	44/76 (58%)
foxi4.2	NP_989265.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Forkhead	125..210	CDD:306709	48/84 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..269		10/59 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	344..363
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020