DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and foxk1

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_956196.1	Gene:	foxk1 / 334470	ZFINID:	ZDB-GENE-030131-6402	Length:	639	Species:	Danio rerio

Alignment Length:	215	Identity:	65/215 - (30%)
Similarity:	99/215 - (46%)	Gaps:	36/215 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 PISKHNSGSS------------------FSSCSSSSSNSSSDSMAAKSNAKPAFTYSALIVMAIW 72
            |.|...:|||                  .:...|.....::...:.|..:||.::|:.|||.||.
Zfish   208 PASPRGAGSSGYRYGRNITSDLQLAAEYAAKAVSEQRTEATGGDSPKDESKPPYSYAQLIVQAIS 272

  Fly    73 SSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDPY 137
            |:.:::||||||...|..::|||||....||||||||||||.:|::|||:.::||:|.:|.:||.
Zfish   273 SAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRVDPS 337

  Fly   138 AEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGPYIKAHSAYFPIMDHQHHA 202
            :| ..:.|...|.||..            |....|.|:......:.|....||...     ..|:
Zfish   338 SE-AKLVEQAFRKRRQR------------GVSCFRTPFGPLSSRSAPASPTHSGLL-----SPHS 384

  Fly   203 AMVQHYQAMMHRYQMMPHPH 222
            :.:|..:.:......:.|.|
Zfish   385 SGLQTPECLSREGSPVSHEH 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	41/76 (54%)
foxk1	NP_956196.1	FHA	23..165	CDD:224630
		FHA	68..152	CDD:238017
		Forkhead	258..344	CDD:278670	44/86 (51%)
		Cyto_heme_lyase	370..>465	CDD:279589	7/40 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820