Protein Alignment fd19B and FOXA1

DIOPT Version :9

• Sequence 1: NP_608369.1
• Gene: fd19B / 33010
• FlyBaseID: FBgn0031086
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_004487.2
• Gene: FOXA1 / 3169
• HGNCID: 5021
• Length: 472
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 74/265 - (27%)
• Similarity: 105/265 - (39%)
• Gaps: 57/265 - (21%)

  Fly    37 SSCSSSSSNSSSDSMAAK---SNAKPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTR 98
            |:...|.:....|:...|   .:|||.::|.:||.|||..:..|.||||.|.:||.|.|||||..
Human   146 SNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQN 210

  Fly    99 KSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDPYAEDL-SIGETTGRLRRSNWQQNTGA- 161
            :..|||||||:||.|..||:|.|:.|.||:|.||.|.|.:.:: ..|....|.:|...::..||
Human   211 QQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAG 275

  Fly   162 --------------------RPKVTGHPYQRMPYYGHGHGNGPYIKAHSAYFP-----IMDHQHH 201
                                .|....:|....|.:...||....::...|..|     .:||...
Human   276 GGGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGA 340

  Fly   202 AAMVQHYQAMMHRYQMMP---------------HPHHHQHQHQHQHPHSHFIQQSKPLHIQEPYH 251
            .|.....:.........|               ||.|....|:.|            ||::...|
Human   341 TATGGASELKTPASSTAPPISSGPGALASVPASHPAHGLAPHESQ------------LHLKGDPH 393

  Fly   252 HTRYH 256
            ::..|
Human   394 YSFNH 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	42/76 (55%)
FOXA1	NP_004487.2	Forkhead_N	17..169	CDD:369872	4/22 (18%)
		FH_FOXA1	157..268	CDD:410812	50/110 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	269..392		20/134 (15%)
		HNF_C	398..461	CDD:401339	1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910