DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and Foxj3

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001101441.1	Gene:	Foxj3 / 313554	RGDID:	1311770	Length:	622	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	105/414 - (25%)
Similarity:	144/414 - (34%)	Gaps:	173/414 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 SLLSVD-----------KKEESPISKHNSG-SSFSSCSSSSSNSSSDSMAAKSNAKPAFTYSALI 67
            ||.|:|           :|.::..:.|.:| |..::....::....:.:....:.||.::|::||
  Rat    23 SLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLI 87

  Fly    68 VMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYW 132
            ..||.||.:|::|||.|.:||.|||||||...|.|:||||||||||..|::|||:.||||:|.||
  Rat    88 TFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYW 152

  Fly   133 ALD------------------------PYAED-----------------LSIGETTGRLRRSNWQ 156
            |:|                        ||:.|                 |:|...|.::...|..
  Rat   153 AIDTNPKEDTLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTD 217

  Fly   157 QNTGARPK----------------------------VTGHPY--------QRMPYYG-------- 177
            |:....|:                            ||.||.        |:.|.|.
  Rat   218 QDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQSLTPQQQPQYNLPERDKQL 282

  Fly   178 ----------------------------------------HGHGNGPYIKAHSAYFPIMDHQH-- 200
                                                    ..|.:..|  .||....:..|.|
  Rat   283 LFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSY--QHSPSSTVTSHPHSN 345

  Fly   201 -------HA----------AMVQHYQAMMHRYQMMPHPHHH-----QHQHQHQHPHSHFIQQS-- 241
                   |:          |.|......||. |..||..|.     ||..:.|||.||..|.|
  Rat   346 QSSLPNNHSGLSATGSNSVAQVSLSHPQMHT-QPSPHTPHRPHGLPQHPQRPQHPASHPQQHSQL 409

  Fly   242 KPLHIQEP------YHHTRYHLHQ 259
            :|.|.|.|      .||.. |.||
  Rat   410 QPPHSQHPPPHQHIQHHPN-HQHQ 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	47/76 (62%)
Foxj3	NP_001101441.1	COG5025	<54..345	CDD:227358	71/292 (24%)
Foxj3	NP_001101441.1	FH_FOXJ3	77..155	CDD:410826	47/77 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920