DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and Foxk2

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	XP_006247952.1	Gene:	Foxk2 / 303753	RGDID:	1305408	Length:	650	Species:	Rattus norvegicus

Alignment Length:	196	Identity:	67/196 - (34%)
Similarity:	99/196 - (50%)	Gaps:	35/196 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SVDKKEESPISKHNSGSSF--------SSCSSSSSNS-------SSDSMAAKSNAKPAFTYSALI 67
            ::......|.|...:|||.        |..:..:.||       :|...:.|.::||.::|:.||
  Rat   194 TISAANSCPSSPRGAGSSGYKMGRVIPSDLNLMADNSQPENEKEASGGDSPKDDSKPPYSYAQLI 258

  Fly    68 VMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYW 132
            |.||..:.:|:|||:||...|..|:|||||....||||||||||||.:|::|||:.::||:|.:|
  Rat   259 VQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFW 323

  Fly   133 ALDPYAEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGP-------YIKAHS 190
            .:|| |.:..:.|...|.|          ||:  |.|..|.|.......:.|       .:.|||
  Rat   324 RIDP-ASESKLVEQAFRKR----------RPR--GVPCFRTPLGPLSSRSAPASPNHAGVLSAHS 375

  Fly   191 A 191
            :
  Rat   376 S 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	41/76 (54%)
Foxk2	XP_006247952.1	FHA	41..145	CDD:238017
Foxk2	XP_006247952.1	Forkhead	249..335	CDD:278670	44/86 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820