DRSC/TRiP Functional Genomics Resources

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Protein Alignment fd19B and FOXD3

DIOPT Version :9

Sequence 1:NP_608369.1 Gene:fd19B / 33010 FlyBaseID:FBgn0031086 Length:260 Species:Drosophila melanogaster
Sequence 2:NP_036315.1 Gene:FOXD3 / 27022 HGNCID:3804 Length:478 Species:Homo sapiens


Alignment Length:216 Identity:78/216 - (36%)
Similarity:104/216 - (48%) Gaps:36/216 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 EESPISKHNSGSSFSSCSSSSSNSSSDSMAAKSNAKPAFTYSALIVMAIWSSSEKRLTLSGICKW 87
            ||...|....|:     .|.|:...:.|....|..||.::|.|||.|||..|.:|:|||||||::
Human   111 EEGGASGGGPGA-----GSGSAGGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEF 170

  Fly    88 IADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDPYAEDL----------- 141
            |::.|||||.:...||||||||||||..||::||...:||:|:||.|||.:||:           
Human   171 ISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRK 235

  Fly   142 --------SIGETTGRLRRSNWQQNTGARPKVTGHPYQRMPYYGHGHGNGPYIKAHSAYFPIMDH 198
                    .:.|.|..:.:|....:..|.....| ||.| ||..|.      ..|..||    .|
Human   236 RFKRHQQEHLREQTALMMQSFGAYSLAAAAGAAG-PYGR-PYGLHP------AAAAGAY----SH 288

  Fly   199 QHHAAMVQHYQAMMHRYQMMP 219
            ...||......|:.:.|.:.|
Human   289 PAAAAAAAAAAALQYPYALPP 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fd19BNP_608369.1 FH 58..135 CDD:238016 45/76 (59%)
FOXD3NP_036315.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..136 7/29 (24%)
Forkhead 141..227 CDD:278670 50/85 (59%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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