DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and FOXJ1

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001445.2	Gene:	FOXJ1 / 2302	HGNCID:	3816	Length:	421	Species:	Homo sapiens

Alignment Length:	123	Identity:	56/123 - (45%)
Similarity:	74/123 - (60%)	Gaps:	8/123 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 HNSGSSFSSCSSSSSNSSSDS-------MAAKSNAKPAFTYSALIVMAIWSSSEKRLTLSGICKW 87
            |..|...|||:|.|:.....:       .|...:.||.::|:.||.||:.:|...::|||.|.||
Human    86 HTPGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKW 150

  Fly    88 IADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDP-YAEDLSIG 144
            |.|||.|:|.....||||||||||||..|::|||..|:||:|.:|.:|| |||.|..|
Human   151 ITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSG 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	41/76 (54%)
FOXJ1	NP_001445.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..116		7/29 (24%)
		Forkhead	121..205	CDD:306709	46/83 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	261..302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820