DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fd19B and FOXD4L1

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_036316.1	Gene:	FOXD4L1 / 200350	HGNCID:	18521	Length:	408	Species:	Homo sapiens

Alignment Length:	192	Identity:	76/192 - (39%)
Similarity:	103/192 - (53%)	Gaps:	12/192 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SSFSSCSSSSSNSSSDSMAAKSNAKPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTR 98
            |.|.:...:...|::.|..|:..|||.::|.|||.|||..|..|||||||||.:|:..|||||.:
Human    83 SEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMAILQSPHKRLTLSGICAFISGRFPYYRRK 147

  Fly    99 KSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDPYAEDL-SIGETTGRLRRSNWQQNT-GA 161
            ...||||||||||||..||::||....||:|.||:|||.::|: ..|....|.:|....|.| ||
Human   148 FPAWQNSIRHNLSLNDCFVKIPREPGHPGKGTYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGA 212

  Fly   162 RPKVTGHPYQRMPYYG--HGHGNGPYIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHP 221
            .   ..||:.....:.  |....||.:.|.:...|:.....:.|..:...|::|     |||
Human   213 H---LPHPFPLPAAHAALHNPRPGPLLGAPALPQPVPGAYPNTAPGRRPYALLH-----PHP 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	46/76 (61%)
FOXD4L1	NP_036316.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..54
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	71..104		5/20 (25%)
		Forkhead	107..193	CDD:278670	50/85 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	385..408
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820