DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and unc-130

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_496411.1	Gene:	unc-130 / 174721	WormBaseID:	WBGene00006853	Length:	333	Species:	Caenorhabditis elegans

Alignment Length:	215	Identity:	80/215 - (37%)
Similarity:	116/215 - (53%)	Gaps:	19/215 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RSLLSVDKKEES--PISKHNS-GSSFSSCSSSSSNSSSD-----------SMAA---KSNAKPAF 61
            |||.....::|.  |:.|.|. ..|.||.:.|||:.:.|           ||:.   .|:|||.:
Worm    66 RSLGDEPTEDEDGVPVRKANKRNHSTSSAADSSSDDAKDDDDDDDSTSRKSMSGHRKSSHAKPPY 130

  Fly    62 TYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDP 126
            :|.|||.|:|.:|.||:||||.||::|.:.|.||:.:...||||||||||||..||:|.|...:|
Worm   131 SYIALIAMSILNSPEKKLTLSEICEFIINKFEYYKEKFPAWQNSIRHNLSLNDCFVKVARGPGNP 195

  Fly   127 GRGHYWALDPYAEDLSIGETTGRLRRSNWQQNTGA-RPKVTGHPYQRMPYYGHGHGNGPYIKAHS 190
            |:|:||||||..||:....:..| ||..:::|:.. ...::.||....|:...|....|.:....
Worm   196 GKGNYWALDPNCEDMFDNGSFLR-RRKRYKKNSDTYHEMMSHHPMPFPPFLPQGMPFPPRMMHPM 259

  Fly   191 AYFPIMDHQHHAAMVQHYQA 210
            |..|::.|..:...|.:..|
Worm   260 ANIPMLGHPMNPRAVPNMPA 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	43/76 (57%)
unc-130	NP_496411.1	COG5025	<126..330	CDD:227358	63/155 (41%)
unc-130	NP_496411.1	Forkhead	127..212	CDD:365978	48/84 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820