DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and Foxd2

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_032619.1	Gene:	Foxd2 / 17301	MGIID:	1347471	Length:	492	Species:	Mus musculus

Alignment Length:	212	Identity:	71/212 - (33%)
Similarity:	98/212 - (46%)	Gaps:	50/212 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 KPAFTYSALIVMAIWSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRA 122
            ||.::|.|||.|||..|.:||||||.||::|:..|||||.:...||||||||||||..||::||.
Mouse   129 KPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPRE 193

  Fly   123 LDDPGRGHYWALDPYAEDLSIGETTGRLRRSNWQQNTGARPKVTGHPYQRM-------------- 173
            ..:||:|:||.|||.:.|:....:..| ||..:::.....|....||:..:
Mouse   194 PGNPGKGNYWTLDPESADMFDNGSFLR-RRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGA 257

  Fly   174 ------PYYGHGHGNGPYIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMPHPHHHQHQHQHQH 232
                  .|..:|:|.|..:.|:.|..|                     ...|||        |.|
Mouse   258 FLSSFAAYGAYGYGYGLALPAYGAPPP---------------------GPAPHP--------HPH 293

  Fly   233 PHSHFIQQSKPLHIQEP 249
            ||:.....:.|..:..|
Mouse   294 PHAFAFAATAPCQLSVP 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	45/76 (59%)
Foxd2	NP_032619.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	13..125
		Forkhead	129..215	CDD:278670	49/85 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..344		1/2 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	394..441
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910