DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd19B and Foxf2

DIOPT Version :9

Sequence 1:	NP_608369.1	Gene:	fd19B / 33010	FlyBaseID:	FBgn0031086	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_034355.2	Gene:	Foxf2 / 14238	MGIID:	1347479	Length:	446	Species:	Mus musculus

Alignment Length:	259	Identity:	83/259 - (32%)
Similarity:	109/259 - (42%)	Gaps:	83/259 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NSGSSFSSCSSSSSNSSSDSMAAKSNA------------------------KPAFTYSALIVMAI 71
            :|.||.:||:||||||.|.|..|..:|                        ||.::|.|||||||
Mouse    49 SSSSSSASCASSSSNSVSASAGACKSAASSGGAGAGSGGTKKATSGLRRPEKPPYSYIALIVMAI 113

  Fly    72 WSSSEKRLTLSGICKWIADNFPYYRTRKSVWQNSIRHNLSLNPFFVRVPRALDDPGRGHYWALDP 136
            .||..||||||.|.:::...||::|.....|:||:|||||||..|:::|:.|..||:||||.:||
Mouse   114 QSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDP 178

  Fly   137 YAEDLSIGETTGRLRRSNWQQNT----------------GARPKVTGHPYQRMPYYGHG-HGNGP 184
             |.:....|.:.|.|...:::..                ||.....|..:|..|....| ||.|.
Mouse   179 -ASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGASLLPQGFDFQAPPSAPLGCHGQGG 242

  Fly   185 YIKAHSAYFPIMDHQHHAAMVQHYQAMMHRYQMMP-------------HPHH-HQHQHQHQHPH 234
            |                           ....|||             |||| |.|...|..|:
Mouse   243 Y---------------------------GGLDMMPAGYDTGAGAPGHAHPHHLHHHHVPHMSPN 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd19B	NP_608369.1	FH	58..135	CDD:238016	41/76 (54%)
Foxf2	NP_034355.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..97		15/47 (32%)
		FH	100..188	CDD:214627	45/88 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	257..278		7/20 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	304..325
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810