Protein Alignment DNAJA1 and CG5504

DIOPT Version :9

• Sequence 1: NP_001530.1
• Gene: DNAJA1 / 3301
• HGNCID: 5229
• Length: 397
• Species: Homo sapiens
• Sequence 2: NP_995932.1
• Gene: CG5504 / 48844
• FlyBaseID: FBgn0002174
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 116/444 - (26%)
• Similarity: 180/444 - (40%)
• Gaps: 101/444 - (22%)

Human     7 YYDVLGVKPNATQEELKKAYRKLALKYHPDKN---PNEGEKFKQISQAYEVLSDAKKRELYDKGG 68
            ||..|||..||..:::||||.:||.|||||.|   |:.|.||:::|:|||||||.:||..||..|
  Fly    66 YYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREYDTYG 130

Human    69 EQAIK--------EGGAGGGFG--------------SPMDIFDMFFGGG---------------- 95
            :.|..        .||..||||              .|.::|...||.|
  Fly   131 QTAENIGRQGGGFPGGGAGGFGPEGFSQSWQFRSSIDPEELFRKIFGEGNFRTNSFDDFADSKFG 195

Human    96 -GRMQRERRGKNVVHQLSVTLEDLYNGATRKLALQKNVI--CDKCEGR----GGKKGAVECCPNC 153
             |:.|.        ..:.:|......|..:.:.:  ||:  |.||.|.    |.|.|.   |..|
  Fly   196 FGQAQE--------MVMDLTFAQAARGVNKDVNV--NVVDQCPKCAGTKCEPGTKPGR---CQYC 247

Human   154 RGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKD 218
            .|||.:  ....||.:   ::|.|..|||..:.|  |..|..|.|:....:::.:.|.:..|:::
  Fly   248 NGTGFE--TVSTGPFV---MRSTCRYCQGTRQHI--KYPCSECEGKGRTVQRRKVTVPVPAGIEN 305

Human   219 GQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNR 283
            ||.:.      .:.|.:...:...:::.|:  |.|.|.|:.....|.|.:|:.|     .|:..:
  Fly   306 GQTVR------MQVGSKELFVTFRVERSDY--FRREGADVHTDAAISLAQAVLG-----GTVRVQ 357

Human   284 TIV----ITSHPGQIVKHGDIKCVLNEGMPIYR-RPYEKGRLIIEFKVNFPENGFLSPDKLSLLE 343
            .:.    |...||....|.    ::..|..:.| ..:..|...:..|:..|....|...:|:|:|
  Fly   358 GVYEDQWINVEPGTSSHHK----IMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIE 418

Human   344 KLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHPRGGVQCQTS 397
            ..    .|:|| |...|:..:      ..|:..:.:|.......|..|...:.|
  Fly   419 AY----AELEE-DTPGQIHGI------ANRKDGSKQATAGASEEPGAGAAAKAS 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJA1	NP_001530.1	PTZ00037	2..394	CDD:240236	115/439 (26%)
		CXXCXGXG motif	134..141		4/10 (40%)
		CXXCXGXG motif	150..157		3/6 (50%)
		CXXCXGXG motif	177..184		4/6 (67%)
		CXXCXGXG motif	193..200		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..397		8/44 (18%)
CG5504	NP_995932.1	DnaJ	63..437	CDD:223560	111/418 (27%)
		DnaJ	65..127	CDD:278647	33/60 (55%)
		DnaJ_zf	227..287	CDD:199908	24/69 (35%)
		DnaJ_C	288..409	CDD:199909	24/137 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910