Protein Alignment DNAJA1 and Droj2

DIOPT Version :10

• Sequence 1: NP_001530.1
• Gene: DNAJA1 / 3301
• HGNCID: 5229
• Length: 397
• Species: Homo sapiens
• Sequence 2: NP_650283.1
• Gene: Droj2 / 41646
• FlyBaseID: FBgn0038145
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 400
• Identity: 246/400 - (61%)
• Similarity: 310/400 - (77%)
• Gaps: 15/400 - (3%)

Human     1 MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRELYD 65
            |||||.|||:||||||||.:||||||||||||||||||||||||||.|||||||||||.||::||
  Fly     1 MVKETGYYDILGVKPNATPDELKKAYRKLALKYHPDKNPNEGEKFKAISQAYEVLSDADKRQVYD 65

Human    66 KGGEQAIKEGGA-GGGFGSPMDIFDMFFG------GGGRMQRERRGKNVVHQLSVTLEDLYNGAT 123
            :|||.|||:||| .|.|.:|||.|:.|||      |||| :||||||:||||:||.||:||||||
  Fly    66 EGGEAAIKKGGADSGDFRNPMDFFEKFFGAGFGGSGGGR-RRERRGKDVVHQMSVQLEELYNGAT 129

Human   124 RKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERIS 188
            |||.||||||||||||||||||::|.|..|||.|::.|:.||.||::|.|:.||.:|.|.||.|.
  Fly   130 RKLQLQKNVICDKCEGRGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQ 194

Human   189 PKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTR 253
            .|||||:|:|||.|||:|:|||||:|||:|||||.|.||||.||..:||||||:||:|:|:.|..
  Fly   195 EKDRCKNCSGRKTVRERKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAH 259

Human   254 RGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKG 318
            .|:||.|.|.:||||||||||:.:.|||:|.:::::.||::::|...||:..|||||::.|.|||
  Fly   260 AGQDLMMKMPLQLVEALCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKG 324

Human   319 RLIIEFKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYED 383
            .|||:|:|.|||  .::|..:..|::.||...||:...:.:|..|.||||.|.|::|.. .||::
  Fly   325 TLIIQFEVIFPE--VINPSVVPTLKQCLPPAPEVDIPIDAEQTVLEDFDPKQRRQQHQR-MAYDE 386

Human   384 DEHHPRGGVQ 393
            |:    ||.|
  Fly   387 DD----GGYQ 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJA1	NP_001530.1	PTZ00037	2..394	CDD:240236	244/398 (61%)
		CXXCXGXG motif	134..141		6/6 (100%)
		CXXCXGXG motif	150..157		4/6 (67%)
		CXXCXGXG motif	177..184		3/6 (50%)
		CXXCXGXG motif	193..200		4/6 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..397		15/41 (37%)
Droj2	NP_650283.1	PTZ00037	2..398	CDD:240236	244/398 (61%)