Protein Alignment DNAJA1 and DnaJ-H

DIOPT Version :9

• Sequence 1: NP_001530.1
• Gene: DNAJA1 / 3301
• HGNCID: 5229
• Length: 397
• Species: Homo sapiens
• Sequence 2: NP_001260431.1
• Gene: DnaJ-H / 34707
• FlyBaseID: FBgn0032474
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 399
• Identity: 148/399 - (37%)
• Similarity: 227/399 - (56%)
• Gaps: 25/399 - (6%)

Human     8 YDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRELYDKGGEQAI 72
            ||||.|.|:||.||:||.|||||.::||||||:.|:|||:||.|||||||.:||.:||:.|.:.:
  Fly     7 YDVLKVAPDATDEEIKKNYRKLAKEFHPDKNPDAGDKFKEISFAYEVLSDPEKRRIYDRYGLKGL 71

Human    73 KEGGAGGGFGSPMDIFDMFF-------GGGGRMQRERRGKNVVHQLSVTLEDLY-NGATRKLALQ 129
            :||..  ||....:.|..:|       .|.||    |.|| ||.::.:|||::| .|..:|:...
  Fly    72 QEGAE--GFSDASEFFAQWFPFDRVSSEGRGR----RNGK-VVVKVELTLEEIYVGGMKKKVEYN 129

Human   130 KNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQSVCMECQGHGERISPKDRCK 194
            :..:|.||.|.||.|.|.|.|..|.|.|.......:|   :....:.|..|.|.|..|....:|.
  Fly   130 RQKLCSKCNGDGGPKEAHESCETCGGAGRAAAFTFMG---LSPFDTTCPTCDGRGFTIRDDKKCS 191

Human   195 SCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLEPGDIIIVLDQKDHAVFTRRGEDLF 259
            .|.|...|.:|...::.:::|.....|:.|..||.|..|.|.||:|:|:.|.:|.:|.||..:|:
  Fly   192 PCQGSGFVEQKMKRDLVVERGAPHMLKVPFANEGHQMRGGEFGDLIVVISQMEHPIFQRRHANLY 256

Human   260 M-CMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIVKHGDIKCVLNEGMPIYRRPYEKGRLIIE 323
            | .::|.:.|||||:......||.|.:.:.::||::::|..||.|...|||::.:..:.|.|.::
  Fly   257 MRDLEINITEALCGYSHCFKHLDGRNVCLRTYPGEVLQHNQIKMVRGSGMPVFNKATDSGDLYMK 321

Human   324 FKVNFPENGFLSPDKLSLLEKLLPERKEVEETDEMDQVELVDFDPNQERRRHYNGEAYEDDEHHP 388
            |||.||:|.|.:..:|::||.|||.|:.:......::|::.|:.|...::...:|::...:
  Fly   322 FKVKFPDNDFATAPQLAMLEDLLPPRQPIVIPKNAEEVQMTDYKPQPRQQEDEDGQSSHFE---- 382

Human   389 RGGVQCQTS 397
              ||||||:
  Fly   383 --GVQCQTA 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJA1	NP_001530.1	PTZ00037	2..394	CDD:240236	144/394 (37%)
		CXXCXGXG motif	134..141		4/6 (67%)
		CXXCXGXG motif	150..157		3/6 (50%)
		CXXCXGXG motif	177..184		3/6 (50%)
		CXXCXGXG motif	193..200		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	352..397		9/44 (20%)
DnaJ-H	NP_001260431.1	DnaJ	1..363	CDD:223560	139/365 (38%)
		DnaJ	5..64	CDD:278647	38/56 (68%)
		DnaJ_C	106..329	CDD:199909	76/225 (34%)
		DnaJ_zf	134..197	CDD:199908	22/65 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0712
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012379at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820