Protein Alignment Dop2R and Octbeta1R

DIOPT Version :9

• Sequence 1: NP_001014758.2
• Gene: Dop2R / 33007
• FlyBaseID: FBgn0053517
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_001262843.1
• Gene: Octbeta1R / 42652
• FlyBaseID: FBgn0038980
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 691
• Identity: 162/691 - (23%)
• Similarity: 236/691 - (34%)
• Gaps: 305/691 - (44%)

  Fly   243 LLQRTATVARETLGNRTAPSTTSYDGGGSGDVG------------------VAGGLAGTAGGGVG 289
            ||||...::..|.......|.:|:.||.:..:.                  :|.||...   |:|
  Fly     3 LLQRLQAMSATTTRTILEGSISSFGGGTNEPLASKIPVLEESASHARYLKFIADGLIDE---GLG 64

  Fly   290 GAGGSGGSTFMLLLENFNDYFPNYNGSTVSGTSTIAPGVA--ITGSRGSGLLLEQNLTGLYLDGY 352
            .|.|||.|.                  .||....:| |.|  |..|.||
  Fly    65 SAVGSGSSI------------------AVSVEDVVA-GQAQDIQASEGS---------------- 94

  Fly   353 RLNCTNETLNLTDSCGELRVVDHNYWALILILFPIL-TLFGNILVILSVCRERSLQTVTNYFIVS 416
                |::    .|....|.:|   :....:|.|.|| .:.||:|||:||.|.|.|:.:||||:||
  Fly    95 ----TDD----ADGSSHLALV---FVKCFIIGFIILAAILGNMLVIVSVMRHRKLRIITNYFVVS 148

  Fly   417 LAIADLLVAVVVMPFAVYFLVNGAWALPDVVCDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPI 481
            ||:||:|||:..|.|....:::|.|....|:||.:.:.||..||:||.:|..||:|||.|:.||:
  Fly   149 LAVADMLVALCAMTFNASVMISGKWMFGSVMCDMWNSFDVYFSTASIMHLCCISVDRYYAIVQPL 213

  Fly   482 KYAKHKNSRRVCLTILLVWAISAAIGS--PIVLGLNNTPNR------EPDVCAF-YNADFILYSS 537
            .|......|||.:.:|:|| :|.|:.|  ||..|...|...      .|.:|.| .|..:.:.||
  Fly   214 DYPLIMTQRRVFIMLLMVW-LSPALLSFLPICSGWYTTTENYKYLKSNPHICEFKVNKAYAIVSS 277

  Fly   538 LSSFYIPCIIMVFLYWNIFKALRSRARKQRAARKPHLSELTGGSVIENIAQTRRLAETALDSSRH 602
            ..||:||.|:|:.:|:.|:         |.|.|:            |.:....::|...|:....
  Fly   278 SMSFWIPGIVMLSMYYRIY---------QEADRQ------------ERLVYRSKVAALLLEKHLQ 321

  Fly   603 ASRILPDEAATNTASGSNEEEDENAISPDIDDCHVIVNDKSTEFMLATVVEETGNSVVAQITTQP 667
            .|:|
  Fly   322 ISQI------------------------------------------------------------- 325

  Fly   668 QLVVADPNGNHDSGYAASNVDDVLAGVAPASASAATSAAPRSSGSPPDSPLPSGATLQRSSVSSQ 732
                                                             |.|
  Fly   326 -------------------------------------------------PKP------------- 328

  Fly   733 RRPTGDDSPKRGEPALRSVGVDNSSVAMKPLSFVRYGVQEAMTLARNDSTLSTTSKTSSRKDKKN 797
             ||              |:.|:.|::
  Fly   329 -RP--------------SIQVEQSTI--------------------------------------- 339

  Fly   798 SQASRFTIYKVHKASKKKREKSSAKKERKATKTLAIVLGVFLFCWLPFFSCNIMDAMCAKFKKDC 862
                                 |:.::||||.:||.|::..||.||||||...|:.::|    ..|
  Fly   340 ---------------------STMRRERKAARTLGIIMSAFLICWLPFFLWYIVSSLC----DSC 379

  Fly   863 -RPGLTAYMMTTWLGYINSFVNPVIYTIFNPEFRKAFKKIM 902
             .|.|...:: .|:||.||.:||:||..||.:||.||||.:
  Fly   380 ITPRLLVGIL-FWIGYFNSALNPIIYAYFNRDFRAAFKKTL 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop2R	NP_001014758.2	7tmA_D2-like_dopamine_R	376..>565	CDD:320181	77/198 (39%)
		TM helix 1	377..403	CDD:320181	11/26 (42%)
		TM helix 2	410..436	CDD:320181	15/25 (60%)
		TM helix 3	448..478	CDD:320181	15/29 (52%)
		TM helix 4	490..513	CDD:320181	11/24 (46%)
		TM helix 5	529..558	CDD:320181	11/28 (39%)
		7tm_GPCRs	<822..898	CDD:333717	33/76 (43%)
		TM helix 6	825..850	CDD:320095	14/24 (58%)
		TM helix 7	866..891	CDD:320095	10/24 (42%)
Octbeta1R	NP_001262843.1	7tm_4	112..>231	CDD:304433	54/118 (46%)
		7tm_1	124..404	CDD:278431	116/504 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24248
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940