Protein Alignment Dop2R and dop-4

DIOPT Version :9

• Sequence 1: NP_001014758.2
• Gene: Dop2R / 33007
• FlyBaseID: FBgn0053517
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_508238.2
• Gene: dop-4 / 183715
• WormBaseID: WBGene00016872
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 154/557 - (27%)
• Similarity: 254/557 - (45%)
• Gaps: 149/557 - (26%)

  Fly   375 HNYWALILILFPILTLFGNILVILSVCRERSLQTVTNYFIVSLAIADLLVAVVVMPF-AVYFLVN 438
            |...|:.|....:||:.||.||:::||.::.|:..|.|.|:|||||||:|.|:|||. :::.:.|
 Worm    42 HPLLAIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIAN 106

  Fly   439 GAWALPDVVCDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIKYAKHKNSRRVCLTILLVWAIS 503
            ..|....::||.:.|||::.||:||:||..||:|||:|...||.|....:.||:.:.||.||.:|
 Worm   107 HTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLS 171

  Fly   504 AAIGSP-IVLGLNNTPN--REPDVCAFYNAD-FILYSSLSSFYIPCIIMVFLYWNIF-------K 557
            |.:..| |:....::|:  .:...|.|.::. ::.:|||.|||||..:::|.|..::       |
 Worm   172 AILSFPGIIWWRTSSPHLYEDQSQCLFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSK 236

  Fly   558 ALRSRAR----KQRAARKPHLSELTGGSVI--ENIAQTR------RLAETALDSSR-HA---SRI 606
            .:|...:    |:|..:|   |.....|::  ||....|      :.:.::|.:|| ||   :|:
 Worm   237 GMRMGIKTVSIKKRNGKK---SNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRL 298

  Fly   607 LPDEAATNTASGSNEEEDENAISPDIDDCHVIVNDKSTEFMLATVVEETGNSVVAQITTQPQLVV 671
            |..:.:..:                       :||:.         |...|:.|.|
 Worm   299 LLKQVSCKS-----------------------LNDRG---------EHNNNNTVRQ--------- 322

  Fly   672 ADPNGNHDSGYAASNVDDVLAGVAPASASAATSAAPRSSGSPPDSPLPSGATLQRSSVSSQRRPT 736
                             .:|.|               :.|...||          .|.||||...
 Worm   323 -----------------PLLRG---------------TEGCHSDS----------ISRSSQRNFR 345

  Fly   737 GDDSPKRGEPALRSVGVDNSSVAMKPLSFVRYGVQEAMTLARNDSTLSTTSKTSSRKDKKNSQAS 801
            |.:.         ::|.:.||      :.::....:.|:|:.| |.:..||..|:|:.....:.|
 Worm   346 GRNV---------TIGSNCSS------TLLQVDQPDRMSLSSN-SQMVMTSPLSTRRKLNVREKS 394

  Fly   802 RFTIYKVHKASKKKREKSSAKKERKATKTLAIVLGVFLFCWLPFFSCNIMDAMCAKFKKDCRPGL 866
            |..:..||              |::|.:||:||:|.|:.||.|||....:.|.|    :.|....
 Worm   395 RQMMRYVH--------------EQRAARTLSIVVGAFILCWTPFFVFTPLTAFC----ESCFSNK 441

  Fly   867 -TAYMMTTWLGYINSFVNPVIYTIFNPEFRKAFKKIM 902
             |.:...||.|::||.:||:||:.|:.:||:|||:|:
 Worm   442 ETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQIL 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dop2R	NP_001014758.2	7tmA_D2-like_dopamine_R	376..>565	CDD:320181	73/204 (36%)
		TM helix 1	377..403	CDD:320181	10/25 (40%)
		TM helix 2	410..436	CDD:320181	15/26 (58%)
		TM helix 3	448..478	CDD:320181	17/29 (59%)
		TM helix 4	490..513	CDD:320181	10/23 (43%)
		TM helix 5	529..558	CDD:320181	10/36 (28%)
		7tm_GPCRs	<822..898	CDD:333717	29/76 (38%)
		TM helix 6	825..850	CDD:320095	12/24 (50%)
		TM helix 7	866..891	CDD:320095	10/25 (40%)
dop-4	NP_508238.2	7tm_4	53..>245	CDD:304433	71/191 (37%)
		7tm_1	59..463	CDD:278431	140/523 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910