DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17003 and Atat1

DIOPT Version :9

Sequence 1:	NP_608365.1	Gene:	CG17003 / 33006	FlyBaseID:	FBgn0031082	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001136216.1	Gene:	Atat1 / 73242	MGIID:	1913869	Length:	421	Species:	Mus musculus

Alignment Length:	221	Identity:	91/221 - (41%)
Similarity:	124/221 - (56%)	Gaps:	30/221 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VEFAFDIKHLFPQSIIRVQAHSLRPKVTQCRRYAQTERGKSTMTSCRL---SEILNI---MGKLS 60
            :||.||:..|||:.|..:..| |||..          |...|.|..|:   .:|:.|   :||.|
Mouse     1 MEFPFDVDALFPERITVLDQH-LRPPA----------RRPGTTTPARVDLQQQIMTIVDELGKAS 54

  Fly    61 ADAQGLCHAVTSADKLASDQ-VVYLMAD---KAAGHWEITGLLKVGTKDLFVFDQGGCYRRLNQT 121
            |.||.|...:|||.::.|:: |:|::.|   :.||...|.|.||||.|.|||.|....:..: :.
Mouse    55 AKAQHLPAPITSALRMQSNRHVIYILKDTSARPAGKGAIIGFLKVGYKKLFVLDDREAHNEV-EP 118

  Fly   122 PAILDFYVHESRQRCGQGKLLFEWMLEKQGWSAHKCTVDRPSNKMLAFMAKHYGLVRTIPQGNNF 186
            ..|||||:|||.||.|.|:.||:.||:|:....|:..:||||.|:|.|:.|||.|..|:||.|||
Mouse   119 LCILDFYIHESVQRHGHGRELFQHMLQKERVEPHQLAIDRPSPKLLKFLNKHYNLETTVPQVNNF 183

  Fly   187 VLYEGFF---DDPITTCKSASGLQAT 209
            |::||||   ..|.|     |.|:||
Mouse   184 VIFEGFFAHQHRPPT-----SSLRAT 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17003	NP_608365.1	Mec-17	84..194	CDD:283063	54/115 (47%)
Atat1	NP_001136216.1	Mec-17	79..190	CDD:283063	52/111 (47%)
		Acetyl-CoA binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03130	124..137		8/12 (67%)
		Acetyl-CoA binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03130	160..169		4/8 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..235		6/14 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..284
		Required for AP2A2-binding	308..387
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	342..421
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849247
Domainoid	1	1.000	136	1.000	Domainoid score	I4906
eggNOG	1	0.900	-	-		E1_KOG4601
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005717
OrthoInspector	1	1.000	-	-		otm43190
orthoMCL	1	0.900	-	-		OOG6_103430
Panther	1	1.100	-	-	O	PTHR12327
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.700