DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17003 and atat1

DIOPT Version :9

Sequence 1:	NP_608365.1	Gene:	CG17003 / 33006	FlyBaseID:	FBgn0031082	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001315193.1	Gene:	atat1 / 406389	ZFINID:	ZDB-GENE-040426-2120	Length:	453	Species:	Danio rerio

Alignment Length:	253	Identity:	83/253 - (32%)
Similarity:	121/253 - (47%)	Gaps:	55/253 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VEFAFDIKHLFPQSIIRV--------QAHSLRPKVTQCRRYAQTERGKSTMTSCRLSEILNIMGK 58
            ::|.:|:..|||:.|..:        :||.....:.|                  ::.:::.:||
Zfish     1 MDFPYDLNALFPERISVLDSNLSAGRKAHGRPDPLPQ------------------VTTVIDELGK 47

  Fly    59 LSADAQGLCHAVTSADKL-ASDQVVYLMAD--KAAGHWEITGLLKVGTKDLFVFDQGGCYRRLNQ 120
            .|:.||.|...:|||.|| |:...:||:.|  :..|...|.|.||||.|.||:.||.|.:  |..
Zfish    48 ASSKAQQLPAPITSAAKLQANRHHLYLLKDGEQNGGRGVIVGFLKVGYKKLFLLDQRGAH--LET 110

  Fly   121 TP-AILDFYVHESRQRCGQGKLLFEWMLEKQGWSAHKCTVDRPSNKMLAFMAKHYGLVRTIPQGN 184
            .| .:|||||.|:.||.|.|..||::||:.:.....:...||||.|.|:|:.|.|.|..::||.|
Zfish   111 EPLCVLDFYVTETLQRHGYGSELFDFMLKHKQVEPAQMAYDRPSPKFLSFLEKRYDLRNSVPQVN 175

  Fly   185 NFVLYEGFFD-------DPIT--------------TCKSASGLQAT--GSGCRSRSQG 219
            |||::.|||.       .|:|              :.|.|.|...|  .:|.||.|.|
Zfish   176 NFVVFAGFFQSRSGTPPSPLTDQGMYGFFGPTEKSSPKKARGRDQTLFANGKRSGSGG 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17003	NP_608365.1	Mec-17	84..194	CDD:283063	49/112 (44%)
atat1	NP_001315193.1	Mec-17	74..185	CDD:283063	49/112 (44%)
		Acetyl-CoA binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03130, ECO:0000269\|PubMed:23105108, ECO:0000269\|PubMed:23128673	118..131		7/12 (58%)
		Acetyl-CoA binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03130, ECO:0000269\|PubMed:23105108, ECO:0000269\|PubMed:23128673	154..163		4/8 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594827
Domainoid	1	1.000	123	1.000	Domainoid score	I5540
eggNOG	1	0.900	-	-		E1_KOG4601
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	103	1.000	Inparanoid score	I4952
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005717
OrthoInspector	1	1.000	-	-		otm26579
orthoMCL	1	0.900	-	-		OOG6_103430
Panther	1	1.100	-	-	O	PTHR12327
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4476
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.780