Protein Alignment Nep3 and ece2b

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: XP_073779419.1
• Gene: ece2b / 793465
• ZFINID: ZDB-GENE-131120-140
• Length: 800
• Species: Danio rerio
• Alignment Length: 833
• Identity: 344/833 - (41%)
• Similarity: 499/833 - (59%)
• Gaps: 97/833 - (11%)

  Fly     1 MTRYKQTEFTEDDSSSI-----------------GGIQLNEATGHTGMQIRYHTARATWNWRSRN 48
            |:.||:..|.|:|.:.:                 |||||....|.                  |.
Zfish    18 MSNYKRATFEEEDGTDVPVDGAISPDSVEVGFRKGGIQLFGPLGR------------------RT 64

  Fly    49 KTEKWLLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASS 113
            :.|       .|:|..:...|:.||       .....|.|:.::....|    .||.:.|:..:|
Zfish    65 QLE-------VVLAGLLLASLLALF-------GCAVTLGVRYNRDPARS----ICLTEACVTVAS 111

  Fly   114 EILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSD 178
            :|::::|.:.|||.|||.|:|..|::.||:|:|:|.|.||..:...||.:::::||....:..|:
Zfish   112 KIVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSE 176

  Fly   179 AERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFN 243
            ||||.:.||.|||: ::.:|:|||:|:.||:.:|||||:|:| ::..|:.  ..|||:...|...
Zfish   177 AERKTQSYYLSCLN-EQRIEELGAQPLMDLITKIGGWNITES-WDKENFL--DVLKIISGPYRAQ 237

  Fly   244 CLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESD 308
            ..|..::..|.|||:.:|||:||.||.||:.|||.|||  :.|||..|::||.::.:|||.:::.
Zfish   238 PFFTVSVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKT--NEKVLKAYLDYMVELGLLLGGDKNS 300

  Fly   309 ARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVT 373
            .|.||..:::||..|||||:|.::||:||.:||.:.:..|..|||.:.|.|:.::.:..:  .:.
Zfish   301 TRGQMQQILDFETALANITVPQDERRDEEKIYHKITIADLQVLAPAIEWLDYLNSVLSPL--ELN 363

  Fly   374 DDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALM 438
            |.|.|||||.::::.:|::|.|.:.:     .||||::|..|:...|.|.:.|.:|...:.::|.
Zfish   364 DTEPVVVYAKEYMQQVSELINKTDHS-----LLNNYMIWNLVQKGASSLDQRFENAQDKLLESLY 423

  Fly   439 GSDGG-EEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESK----------PA-------------- 478
            |:... ...|:.|:.:|::.:|||:||:||:..|..:||          |:
Zfish   424 GTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKQSKEIDLNGGAFLPSCGRNVNSTVHNLMF 488

  Fly   479 -----AEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAEL 538
                 ||.||.|||.|||..|.:|.|:|:|||:.|.:||:.|.|||||||:|||..|||..|...
Zfish   489 SVITQAEGMINEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGY 553

  Fly   539 NITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFF 603
            .:|.:.:|:|.|....::.:....:|.:|.|:..|.|||.||||||.||||.|||||||||.||:
Zfish   554 EVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFY 618

  Fly   604 DINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYK 668
            ..::||:||||.:|||||||||||||||||||||.||:..||.:.|:|.|..::||:..||:.|.
Zfish   619 AQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYT 683

  Fly   669 MNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSS 733
            :||..:||||||||||||||||||||||| |:...::.:..:||.:|||:.|||||.|||||||.
Zfish   684 INGEHINGKQTLGENIADNGGLKAAYHAY-RSWVQKNGEEKRLPAVNLTNDQLFFVGFAQVWCSV 747

  Fly   734 TTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            .|.|:....:..|||||.::||||||||..||||.|||..|..||...:||||
Zfish   748 RTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGHRCEVW 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	312/690 (45%)
ece2b	XP_073779419.1	None