Protein Alignment Nep3 and ece1

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_001071260.3
• Gene: ece1 / 777750
• ZFINID: ZDB-GENE-061110-100
• Length: 766
• Species: Danio rerio
• Alignment Length: 796
• Identity: 316/796 - (39%)
• Similarity: 486/796 - (61%)
• Gaps: 54/796 - (6%)

  Fly     1 MTRYKQTEFTEDDSSSIGGIQLNEATGHT-GMQIRYHTARATWNWRSRNKTEKWLLITTFVMAIT 64
            |:.||:....|::....|    ::...|| .||:..........|..:..:|:.|::....:::.
Zfish    15 MSTYKRATLEEEELLDTG----SDGIYHTSSMQVGVQRGLGLRCWAEKTHSERKLVVLVCALSVA 75

  Fly    65 IFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDF 129
            :|..::.|..                |.|:...|   .||::.|:..:|.:|.|:|.:||||.||
Zfish    76 LFICIVSLGL----------------HYKESHPG---LCLSEPCVSVASAVLGSLDRSVDPCQDF 121

  Fly   130 YGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDAD 194
            |.::|..|::.||:|||||.||.|..|.:.|..:::|:||..:....|.||:||:.||::|:: :
Zfish   122 YNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMN-E 185

  Fly   195 EHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSR 259
            ..:|:|||||:.||:.|.|||.: |..:...|:.  ..|:|:...:..:..|...:..|.|:|:.
Zfish   186 SKIEELGAKPLQDLINQTGGWGL-KGPWEKDNFQ--EVLRIVSANFRTSPFFTVFVSTDSKSSNS 247

  Fly   260 HVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLA 324
            ::||:||.||.||:.:||.|||.| .|.||.|:.::.::.||||.::..::..|..:|.||..||
Zfish   248 NIIQVDQSGLGLPSREYYLNKTAN-EKYLNAYLNFLVELGVLLGGSQDTSQKMMEEIIKFETTLA 311

  Fly   325 NITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNL 389
            |||:|..:||:||.:|:.:|.::|:.|||.::|.....:....|  .:.|.|.|||||.::|:.:
Zfish   312 NITVPQVERRDEEKIYYKIQAKELATLAPAIDWMPFLSSVFAPV--ELNDSEPVVVYAKEYLQKV 374

  Fly   390 SDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYK-------GVRKALMGSDGGEEIW 447
            |::|     :...|..||||::.:.||.:.|.|.:.|:||.:       |.:|:.|..      |
Zfish   375 SELI-----SNTNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFLEVMYGTKKSCMPR------W 428

  Fly   448 RYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKA 512
            :.|||||::.:|||:||:||:..|..:||...|.|::||:.||:.:|:.::|:|.:|::.|.|||
Zfish   429 KLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKA 493

  Fly   513 NQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTP 577
            :.|.:|:|:|.:|::|.||||.:.:.::..:.||:|.:....::.:....:|.:..|:..|.|||
Zfish   494 DAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTP 558

  Fly   578 QTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNIN 642
            .||||||.||||::|.||||.|.||::...||::|||.:|||||||||||||||||:|||.||:.
Zfish   559 PTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLA 623

  Fly   643 RWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQR--TKSDRD 705
            :||.:.|:|.|..:::|:..|||.|.:|...||||.||||||||||||.|||.||..  .|:..:
Zfish   624 KWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEE 688

  Fly   706 VDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQ 770
            .   .||.|.:.:.|||||.|||||||..|.|::...:..||||||:||||||:||..||:|.|.
Zfish   689 A---SLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFG 750

  Fly   771 CKPGKRMNPTEKCEVW 786
            ||....|||..|||:|
Zfish   751 CKADSPMNPKRKCELW 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	289/669 (43%)
ece1	NP_001071260.3	None