Protein Alignment Nep3 and Nepl21

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 737
• Identity: 211/737 - (28%)
• Similarity: 334/737 - (45%)
• Gaps: 114/737 - (15%)

  Fly    92 QKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIK-NNPIPEGKSTWGTFGK 155
            ::|.|...||....|     ::||...:|...|||:|||.:||..:.: |:.:.....|.|.|..
  Fly    37 KQDTPYMKELLRQAK-----TAEIESFMDQKADPCNDFYAFSCGNYKRINSALSMQVVTTGVFET 96

  Fly   156 LEQ-MNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADE----HMEKL-------GAKPMNDL 208
            |.: :|:.|:: :|..|..|..:..:.|.|.:|||||...|    :.|||       |..|
  Fly    97 LTKGLNRKILK-MLNTPHDSHDTPEDIKVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMP---- 156

  Fly   209 LLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTL-- 271
            ||:...|.     .:..:| :..|.::.: :|....:||..:.:|..:::|:.|.:.|....|
  Fly   157 LLEGSSWQ-----EDDFDW-LNTTARMAY-RYGITPIFGIEVNKDLASNTRNRIYLGQQDFPLEA 214

  Fly   272 -------PTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIP 329
                   .||.|.....:|.:::|..|          ||.....|:.....:|:||..||.   .
  Fly   215 RSMYVDDATAVYRQKYRNNIQRILQRY----------LGVKMDLAKKTAKELIDFEVDLAQ---G 266

  Fly   330 LEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQM-VGRRVTDDEVVVVYAPDFLKNLSDII 393
            |.|......:....||..:.::....:.|...|..:.: :|.|::|.  :..|...:.:||.::|
  Fly   267 LVDESEGLDVGELTQLLTVDEIQRRYSPTLDIDRLLFVSMGERISDQ--IYEYNNRYQQNLVEVI 329

  Fly   394 LKMEQTEEGKITLNNY----LVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDT 454
            .:..     |.|:.||    |:|:.|.|                     .||..|:..:.||..|
  Fly   330 KRTP-----KRTVANYIFFRLIWEFVET---------------------PSDSPEKQMKACVDLT 368

  Fly   455 NNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQN---LTWVDKQTREKAIEKANQIS 516
            .......:..:|.|:..:.:|....:.|..:::..|...|::   |.|:::.||..|:.|...::
  Fly   369 KKYFAKNLDNMFYRRYNNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRNLAMAKLQAMT 433

  Fly   517 DMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVN 581
              :...:|..|  ...:::||||:..:.|.||....::...|...:.|.:|......|.     .
  Fly   434 --LEVNNYADD--NFTEEFAELNLQSDDYVENVRYTSLLGAKQMREMLHKPAKPFEAGS-----Q 489

  Fly   582 AYYTPT----KNQIVFPAGILQTPFF---DINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFG 639
            ..|||.    :|.|..|..:|| ||:   |: .|.::.||.:..::||||.|.|||.||::|:.|
  Fly   490 LSYTPANILIENTIKVPVALLQ-PFYIWSDV-YPNAIMFGTLASLIGHELIHGFDDSGRKFDEKG 552

  Fly   640 NINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAY------Q 698
            |...|||.||...|.::.:|..:||..|..:|..|.......||||||||::.||.||      |
  Fly   553 NSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQ 617

  Fly   699 RTKSDRDVDILK--LPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSN 761
            .|..:...|:.|  ||.|..|..||||:||||.||:........||:..|.|.|.:|||||:|||
  Fly   618 LTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDAHPSVKALQVSTDQHMPGRFRVIGSLSN 682

  Fly   762 MKEFAEVFQCKPGKRMNPTEKC 783
            .:||::.|.|..|..|||:|||
  Fly   683 FEEFSKEFNCPAGSAMNPSEKC 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	203/706 (29%)
Nepl21	NP_651646.2	M13	63..704	CDD:341056	201/704 (29%)