Protein Alignment Nep3 and Nepl19

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 182/774 - (23%)
• Similarity: 321/774 - (41%)
• Gaps: 157/774 - (20%)

  Fly    59 FVMAITIFTLLIVLFTDGGSSDATKHVLHVQP--------------HQKDCPSGNELPCLNKHCI 109
            |.:|..:..||::.....|..    |:|..||              ...|......|..|:|
  Fly     4 FGIAHALLQLLLLHLVGSGRG----HLLTGQPAIDLRIQAREQLISQSNDSAYVQRLMRLSK--- 61

  Fly   110 FASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIR-------NV 167
              |:|:...:....|.|::||.|||..|.:.||..:      .:.:.....||:::       .:
  Fly    62 --SAEMRSYMQQDADACENFYDYSCGNWPQINPAND------AYPRETNFVQLLLKAYSHKQQRL 118

  Fly   168 LEKPAKSFKSD--AERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTK---SGYNVANW 227
            :|:|| :.::|  |..:.|.:|.|||...:..|.|..:.:.:::...|...|..   ..:....:
  Fly   119 MEQPA-NVETDEVAVLRLKEFYASCLLFRQVPEDLYRRQLQEIVADFGRMPVLSLPGQEWPAEEF 182

  Fly   228 TMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYI 292
            ....|:..:..:|.|:.|..:       ..|...|.:.|....||.|        |.:.|..:..
  Fly   183 DWLDTVARIKRQYGFDILLLF-------QQSADRIYVGQPKQILPEA--------NRKAVAEDIA 232

  Fly   293 EYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRR--NEEAMYHPMQLR--QLSKLAP 353
            .::.:   .||.:...|......:..||:|:|.|.:   |||  ....:|.|....  .:|||..
  Fly   233 NHLER---HLGVDPKVAVTTAREITEFEQKIAAIMV---DRRVGVMSKLYTPSDADYVDVSKLTQ 291

  Fly   354 FLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTL 418
            |:.         .::.|.:..:|.:..:.||:|..:.:::     ||.....|.||:
  Fly   292 FVE---------TVLDRELLANESLYQHVPDYLMKIDELV-----TETPPHVLANYV-------- 334

  Fly   419 TSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMI 483
                   |.:..|.     ...:..|.:...|||...::.|..:..:...|.   |.:...:.:.
  Fly   335 -------FNELLKH-----FYYERAESVVEQCVSRVRDLFGELLDHMLFEQY---EDEGTLKDIY 384

  Fly   484 A---EIREAFKMNLQN--LTWVDKQTREKAIEKANQISDMI-GFPDYILDPVELDKKYAELNITP 542
            .   :::.:|:..|||  ..|:..:|||:.:|:.|..|.:| |:.:     |...::|.||::.|
  Fly   385 VVWQQLQRSFRGVLQNSSANWLVPETREQLLEQLNTTSLVINGYAE-----VNFTQRYEELHLKP 444

  Fly   543 NAYFENNIQVAIYNLKSNLKRLDQPVN-KTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPF-FDI 605
            ..|        ::||::.|......|. ||...:|       |.|...:::.|..:||..| :..
  Fly   445 RDY--------LHNLRTILNHQSLRVKVKTQTSVT-------YDPVGKRVLLPVALLQPNFLWSR 494

  Fly   606 NNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMN 670
            ..||::.:|::|.::..:|.|:.:|..:           ||:||...::::..|...||...::|
  Fly   495 YYPKAVRYGSLGTLLAQQLAHSLEDASK-----------WDAKSFAEYSKRKSCFKEQYGRLRLN 548

  Fly   671 GRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDIL---KLPGLNLTHSQLFFVSFAQVWCS 732
            |..|.......||||||..::.|||||:|..::.|...|   .||.|||...:|||:||||:||:
  Fly   549 GHYLPESDLQAENIADNLAIQVAYHAYRRLLAELDPSFLGSESLPQLNLGSRRLFFLSFAQLWCN 613

  Fly   733 STTDETNLLQMEKDPHS-----PSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            ...::.      :|..|     |:..||:|.|||.:.|...|.|....||...:||:::
  Fly   614 DANEQF------RDKQSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQLF 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	166/692 (24%)
Nepl19	NP_651644.1	M13	73..664	CDD:341056	166/692 (24%)