Protein Alignment Nep3 and Nepl18

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 753
• Identity: 185/753 - (24%)
• Similarity: 316/753 - (41%)
• Gaps: 138/753 - (18%)

  Fly    73 FTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQW 137
            |.|..:||..|.:: ||.                    ..:|:...:...|.||||||.::|..|
  Fly    29 FADDLTSDYAKKII-VQA--------------------KVAEMKTMMKPEVSPCDDFYTHACGNW 72

  Fly   138 IKNNP--------------IPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYE 188
            .::||              |.:|         .::..|.::|      |...:|:.|:|.:.:|.
  Fly    73 HRHNPAQLLGDVMTDNFKLISKG---------FDRRLQRLLR------ANDLQSELEKKMQRFYM 122

  Fly   189 SC--LDADEHMEKLGAKPMNDLLLQIGGW-NVTKSGYNVANWTMGHTLKILHNKYNFNCLFGWAI 250
            ||  :..|:...||.   :.:::.:.|.. .:..:.:|.::::...|:..:.:||....:.|..|
  Fly   123 SCNLVHRDDVHYKLA---LENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEI 184

  Fly   251 GEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG 315
            ..|.:|:|.:.:.|.|     |.....|.:..|    |.|.:.....:....|.:.|.|:.....
  Fly   185 MHDIRNTSVNRVYISQ-----PDFKTINTRLTN----LMEEVRTSMDLQQYFGLSSSVAKHTAEQ 240

  Fly   316 VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEV--- 377
            :...|:..::........:...::|....|::        .::||. |..:.:|..:.::.:
  Fly   241 LTELERTFSSGGSGAATLQESLSLYTVADLQE--------KYSDHL-NFTEFLGLILGEENIPKS 296

  Fly   378 VVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDG 442
            :.:|..::   |...:|.|..|.  ..|..||::|:.:...       ..||..
  Fly   297 LYIYDEEY---LDKALLTMRSTP--LATQANYVLWKLLEDF-------LVDAQP----------- 338

  Fly   443 GEEIWRYCVSDTNNVVG-FAVGAIFVRQAFHGESKPAAEQMI----AEIREAFKMNL--QNLTWV 500
             :::.::|...|....| .|..|::.|.     ..|..|..:    .:|:..|:..|  ..|.|:
  Fly   339 -KDMVKWCTESTKKYFGKLAEHAVYKRY-----RNPDVESEVHKIWDQIKGIFRQRLLGDKLDWI 397

  Fly   501 DKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLD 565
            ...||..||||..::.  :....|  |....:..|.|:.|....|..|..|:.|......:.|::
  Fly   398 SNATRTLAIEKLERMH--LNINSY--DEENFENVYGEVFIDRLNYVSNVQQLLIAKGIRFVARIN 458

  Fly   566 QPVNKTN----WGMTPQTVNAYYTPTKNQIVFPAGILQTPFF-DINNPKSLNFGAMGVVMGHELT 625
            ||.:..:    .|.||.     |...:|.|..|..:||..:| ....|::|.:..:|.::.||:.
  Fly   459 QPADSVDATELLGFTPA-----YNIQENNITIPVALLQPRYFWGDQYPEALKYATLGYLLAHEML 518

  Fly   626 HAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGL 690
            |.|||.||:||..||:..|||.||...|.|:.:|...||..|:..|..|...:...|||||:|||
  Fly   519 HGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKLPESKDQSENIADSGGL 583

  Fly   691 KAAYHAYQRTKSDRDVDILK---LPGLNLTHSQLFFVSFAQVWCSSTTDETNLL----QMEKDPH 748
            |.||.||:.....:..::|:   :.||.....||||:.:||:.|    |:...|    ..:.|.|
  Fly   584 KLAYAAYELWLGQQSEEVLQRETMEGLPFNSRQLFFLGYAQLLC----DDVQFLFQPWVSQSDRH 644

  Fly   749 SPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            :||::||||.|||.:||..||.|.....|:|..||.::
  Fly   645 APSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	176/699 (25%)
Nepl18	NP_651643.1	M13	58..679	CDD:341056	175/698 (25%)