Protein Alignment Nep3 and Nepl16

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 811
• Identity: 171/811 - (21%)
• Similarity: 293/811 - (36%)
• Gaps: 232/811 - (28%)

  Fly    53 WLLITTFV--MAITIFTLLI--------VLFTDGGSSDATKHVLHVQPHQKDC--------PSGN 99
            ||..:..|  ||||..|||:        :||....:.         .|..:||        |:.:
  Fly    95 WLRTSAAVHKMAITSATLLVTTLLVASPILFLISTAP---------SPLPRDCYMDGDRCSPAVS 150

  Fly   100 ELP-CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNP--------------------- 142
            ..| |.:..|...:|.|...::...|||.:|..:||  | :|.|
  Fly   151 APPECSDPICEAVASSIQARLNWNKDPCTEFKKFSC--W-RNTPNKNITNLIEMGNSQKSVDSQM 212

  Fly   143 --IPEGKSTWGTFGKLEQM---------NQLIIRNVLEK-----PAKSF--KSDAERKAKVYYES 189
              :.:.|...|:||.|..:         |..::..:.:.     |..|.  .|.|...||:|
  Fly   213 LYLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYLPVGSVGPSSIAPLIAKIY--- 274

  Fly   190 CLDADEHMEKLGAKPMNDL------------LLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNF 242
                     .||..|:.||            ||.|.|.:.:.:              ||..|..
  Fly   275 ---------DLGPSPLVDLYHDLSYGRRPHILLIISGPSTSST--------------ILERKIR- 315

  Fly   243 NCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANES 307
                 |...:...:..|.       |:....||...|       .|..::.|..:|      :|.
  Fly   316 -----WMSPKAPPSRIRQ-------GVPKLLADLIEN-------FLPYFVSYAQRV------SEK 355

  Fly   308 DARAQMIGVINFEKKLANITIPLEDRR---NEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVG 369
            |.      :..|.|.|..:.:. ..||   :...:|:   :..|..|.|.||||       .::.
  Fly   356 DT------IFEFIKDLNKLQVE-HSRRGFWDSTVLYN---VSSLQDLYPVLNWT-------LLIP 403

  Fly   370 RRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVR 434
            :..:..  :||...|:||.|...:.|...    ::..|:.|:..|::.|......| ....:...
  Fly   404 QNWSGP--IVVRNSDYLKALEYFLTKYPT----RVAHNSLLLLSALQILPRDYPSP-EVCTRSTM 461

  Fly   435 KALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTW 499
            .||........|.::...|..:....| ..||.....|.:..|:.:.  |.:.:...:.:|:.||
  Fly   462 WALPELSSSLYIAQHSSEDLKDTTKRA-EIIFKSLKAHLKRAPSLKG--AALVKLSALKIQSQTW 523

  Fly   500 VDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRL 564
                      |..:..:|::             |....||||...:|:|.::  ||. |:.|:..
  Fly   524 ----------EGFSNTTDLL-------------KSLQPLNITSECWFQNILE--IYK-KNKLEPN 562

  Fly   565 DQPVNKTN---WGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTH 626
            |..:|..:   |.. |.....:|....:.||.|..::..|:|:...|..|::.::||.:..|:..
  Fly   563 DISLNGGSHDAWAY-PIVSTIFYDTLSHSIVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILR 626

  Fly   627 AFDDQGREYDKFGNINRWWDSKSIERFNEKS-ECIARQYSGYKMNGRTLNGKQTLGENIADNGGL 690
            :.                  :||   |:||: .|:....:.:....|.        :.:..:||:
  Fly   627 SI------------------TKS---FDEKAMRCVPHSVNIFSNYSRM--------DILIHSGGM 662

  Fly   691 KAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRV 755
            :.:||: ..:.:.....:.:|||||||.:|:||:..||..|:    |:|.|.:  |.::|....:
  Fly   663 QISYHS-MLSLTGPIKGMARLPGLNLTPTQIFFLVSAQELCA----ESNYLGI--DTNAPEFDNI 720

  Fly   756 IGTL-SNMKEFAEVFQCKPGKRMNPTEKCEV 785
            :|.| :......|||:|..|..:|..:.|.|
  Fly   721 LGWLVAQGGSATEVFKCPSGSMINVQKTCNV 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	148/719 (21%)
Nepl16	NP_001097912.1	GluZincin	176..750	CDD:472708	148/718 (21%)