Protein Alignment Nep3 and Nepl13

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 744
• Identity: 178/744 - (23%)
• Similarity: 316/744 - (42%)
• Gaps: 128/744 - (17%)

  Fly   112 SSEILKSIDVTVDPCDDFYGYSCNQW---IKNNPIPEGKSTWGTFGKL---EQMNQLIIRNVLEK 170
            ::::.|.::::.|||.||:.|:|.||   .|....|:..||.....:.   ||:.||:.:.:..:
  Fly    57 ATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLPPQ 121

  Fly   171 PAKSFKSDAE----RKAKVYYESCLDADEHMEKLGAKPMNDLLLQI----GGW-NVTKSGYNVAN 226
            ...:..|.|.    ||.:.:||||:..:.:     |......|::|    ||. ||..|     |
  Fly   122 HHPNGYSGASMTNVRKVRAFYESCVAVEAN-----ASERRRFLMKILKDNGGLRNVPNS-----N 176

  Fly   227 WTMG----HTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKV 287
            |...    .||..|...|..:.|.|..|..:.:....:.|...:..||:..|::.|.......:|
  Fly   177 WQHNRQWVQTLGELRRNYGLDILLGLEIDLNLQTMKGNTIYFGEPKLTIIPAEHCNALATRGAQV 241

  Fly   288 LNEYIEYMTKVCV-----LLGANESDARAQMIG-VINFEKKLA------NITIPLED-------- 332
            .:|..|.:.:...     ..|.:..:| |:..| :|.||.:|.      :|..|.|:
  Fly   242 RDEVYELVQQQVTENLRDWFGMDTGEA-ARFAGDIIRFEFELCKQMGEQDIQKPEEEFPPAIQAQ 305

  Fly   333 ------RRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVV-------VY--A 382
                  |..:|.:........|::|...:.  :|.|..|.:        ||::       ||  :
  Fly   306 IYGARSRTGQERLRRQKGGMTLTELTSEMG--NHLDFKMLV--------EVILESQYPSQVYLRS 360

  Fly   383 PDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIW 447
            |:::|::...:     ....:||:..|:::.|:..    |::|..:|..  ::|
  Fly   361 PEYVKHVVRTV-----KANNRITVGGYILYVALNE----LNQPPEEAPS--QRA----------- 403

  Fly   448 RYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKA 512
            |.||..|..:....:|.:|.|......:|...:.:..::.:|.:... ::.|:|:..|..|..:.
  Fly   404 RQCVQVTQRLFPQVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQF-HVEWMDENDRRAARTRL 467

  Fly   513 NQISDMIGFPDY-ILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMT 576
            :|.  .:..||| .||..:|..:.:|       .:...:::|   ||....:..:.:...::|..
  Fly   468 SQY--RVSLPDYQSLDLTDLQFQKSE-------DYWRRLEIA---LKYRSHQQFEALRGNDFGQD 520

  Fly   577 PQTVNAY-----YTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYD 636
            ...::|:     .:|.:..::...|:||.|:::...||||.:..:|..:...|..||||:|  ::
  Fly   521 ADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG--WN 583

  Fly   637 KFGNINRWWDSKSIERFNEKSECIARQYSGYKMN--GRTLNGKQTLGENIADNGGLKAAYHAYQR 699
            ........|:..::..:...|||...|||.|..|  |...|..: |.|.|||..||..|::||..
  Fly   584 NHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGEFRNATR-LREIIADGSGLNLAFNAYLA 647

  Fly   700 TKSDRDVDIL------KLPGLNLTHSQLFFVSFAQVWCSSTTDETNLL-QMEKDPHSPSQFRVIG 757
            ....:|..:.      .|..||.|::||||:.|||..|.:..::..:| .|....|:|.::.|.|
  Fly   648 WLEQQDHKLRPLLAKETLSELNFTNTQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPERWDVNG 712

  Fly   758 TLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            .|||..||...|.|..|..||..:||.|:
  Fly   713 PLSNSAEFGREFGCALGTPMNSGDKCLVY 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	175/729 (24%)
Nepl13	NP_651096.1	M13	68..738	CDD:341056	174/728 (24%)