Protein Alignment Nep3 and Nep4

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 786
• Identity: 280/786 - (35%)
• Similarity: 414/786 - (52%)
• Gaps: 133/786 - (16%)

  Fly   119 IDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEK------------- 170
            :|..||||.|||.|:|..|.:.:|||:.|:.:.||..|.:...|::||:|||
  Fly   270 MDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKS 334

  Fly   171 PAKS--FK--------------------------------------------------------- 176
            |.::  ||
  Fly   335 PVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPR 399

  Fly   177 ---------------------------------------SDAERKAKVYYESCLDADEHMEKLGA 202
                                                   .||:.|||..|.||::: ..:.|.|.
  Fly   400 ERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNS-AVLAKRGL 463

  Fly   203 KPMNDLLLQIGGWNVTKSGYNVA--NW-TMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQI 264
            :|::.|:.::|||.|.:|.::.:  || .:..||:    :||.:.|....:|.|.|||..:::|.
  Fly   464 EPLHTLIRELGGWPVLESQWSESNFNWQVLAATLR----RYNNDILIVQWVGADIKNSEENIVQF 524

  Fly   265 DQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIP 329
            ||.||.|||.:|:  ...::.|.|..|..||.:|...:||:::||:.....::.||.:||.||.|
  Fly   525 DQTGLGLPTREYF--LQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAP 587

  Fly   330 LEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIIL 394
            .|.|.|...:|..|.|.||..:.|.:.|..:..:   :..|.|...|.||:||.::   :|.::.
  Fly   588 AEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQS---LQDREVLGTEEVVIYAVEY---MSKLVT 646

  Fly   395 KMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVG 459
            .:::|:..  |::||::|:.||...:.:...|.|..:....||.|.:...:.|:.|::..|..:|
  Fly   647 LLDETDPR--TVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMG 709

  Fly   460 FAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDY 524
            .|||::||.:.|...||....:|..::::||:..|:...|:|..|::.|.||.|.:|..||:||:
  Fly   710 MAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNAMSLKIGYPDF 774

  Fly   525 ILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKN 589
            ||:|.||:.|||.:.|.|..||||.:.|.::..|:...:|.:.||||||...|..|||||:..||
  Fly   775 ILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNAYYSRNKN 839

  Fly   590 QIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFN 654
            ||:|||||||.||:..:.|||||||.:|||:||||||.|||:||.:|:.|||::||...||..|:
  Fly   840 QIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFD 904

  Fly   655 EKSECIARQYSGYKMN--GRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILK--LPGLN 715
            |::.||..|||.|.:.  |..|||:.|.||||||||||:.|:|||||...:...::..  |||||
  Fly   905 ERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSEVSDEILPGLN 969

  Fly   716 LTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPT 780
            :|..||||::|.||||.:...|....::....|||.:|||||||||..:||..|.|..|..|||.
  Fly   970 MTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQ 1034

  Fly   781 EKCEVW 786
            :||.||
  Fly  1035 KKCSVW 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	276/778 (35%)
Nep4	NP_650904.3	M13	274..1038	CDD:341056	276/778 (35%)