Protein Alignment Nep3 and Nepl9

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_609815.1
• Gene: Nepl9 / 35020
• FlyBaseID: FBgn0032613
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 828
• Identity: 145/828 - (17%)
• Similarity: 266/828 - (32%)
• Gaps: 279/828 - (33%)

  Fly    52 KWLLITTFVMAITIFTLL-IVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEI 115
            :|.|  .||    :|.:: ||...:|..||:...|    ....:..||.....|.|..:   .::
  Fly     2 RWKL--QFV----LFAIIQIVRSQNGEDSDSDTEV----EMDSEVESGQFFSHLYKSNL---QQL 53

  Fly   116 LKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTW---GTFGKLEQMNQLIIRNVLEKPAKSFKS 177
            :|..:.::|||||||.::|..:.:..  .|....:   ..:.|.::|      |.......:|::
  Fly    54 VKIKNDSMDPCDDFYAHACGNFDQTK--EENSDDFLPPYLYNKQDRM------NFFTAEVGNFET 110

  Fly   178 DAERKAKVYYESCLDADE-----------HMEKLGAKPMNDLLL------QIGGWNVTKSG---- 221
            ...|.....|..|...:|           |.|::    ::::..      .:..|...|..
  Fly   111 IPGRLISQLYTECRKREERNVFTPTRLTSHWERM----LDEIPFLARHKEVLSSWPFLKHQWERR 171

  Fly   222 --YNVANWTM------GHTL-KILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPT-ADY 276
              |...||.:      .|.| .:||..:..:.::...:.|                |..|: ||:
  Fly   172 RLYGQLNWIVLSAQLAAHGLPTLLHIYFALDTIYVSPMEE----------------LPCPSIADF 220

  Fly   277 YNNKTD----NHRKVLNEYIEYMTKVC----------------------------VLLGANESDA 309
            .::.:|    .|.:|.......|..:|                            :||..|..|.
  Fly   221 QSSLSDVLEGRHHQVSRIISHEMRVLCREMRGELPLVRSLSQNTRTNTSRPGEEQLLLDENTMDY 285

  Fly   310 RAQMIGVINF-EKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVT 373
            ..|....:|| |::|..            |...|:.:.::::....|..|
  Fly   286 FQQYFAALNFSEERLVG------------ARKFPLDVEKITQAWEVLRHT--------------- 323

  Fly   374 DDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALM 438
              |..:||                          ||::|||...|.      :.|.|:
  Fly   324 --ETRIVY--------------------------NYVMWQAREQLR------YPDCYR------- 347

  Fly   439 GSDGGE-----EIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQM-IAEIREAFKMNLQNL 497
            .|:..|     |.|::.|               :|:....|...|:.|: ....::..:..|...
  Fly   348 VSEEFERLLHAEYWQWHV---------------LRRHLSREVALASYQLHTTRFQKLRRSKLSRR 397

  Fly   498 TWVDKQTREKAIEKANQISDMI-GFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNL 561
            .|..........:|..|::.:: ...:..|:..||::.|..|.:..|:::.|.:.:....|:.:.
  Fly   398 DWYGHLWPASVEKKELQVARILQNHAENYLNITELNENYEGLKLEKNSFYANLLILRRAQLRHSF 462

  Fly   562 -------KRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVV 619
                   :.::||              ||         |....|......::.|....:...|:.
  Fly   463 VSPYVDEEDVNQP--------------AY---------FLRHFLHFVLLSLHRPTYHYYATHGLE 504

  Fly   620 MGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENI 684
            :..|.....|..| .|.....:.|    :|.:.::.|...|.|....::               |
  Fly   505 LWRESRLLLDTDG-HYTAMDCLER----QSFQHYDAKLAPIYRPLGSHE---------------I 549

  Fly   685 ADNGGLKAAYHAYQRTKSD------------RDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDE 737
            |:   :...|.::|.:.:|            .:..:|...||| .|..||: :.||..|:..| |
  Fly   550 AE---IFQFYRSFQYSLTDYHFWLQGERFAFAETFVLDYFGLN-PHRVLFY-AVAQQLCNRQT-E 608

  Fly   738 TNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEV 785
            ....|:.:.            ..|:.||.|.|:|...|.|||..:|.:
  Fly   609 IFAAQLNRG------------YMNLPEFQEAFKCGAEKAMNPPSRCMI 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	128/753 (17%)
Nepl9	NP_609815.1	GluZincin	62..642	CDD:472708	128/751 (17%)