Protein Alignment Nep3 and Nepl5

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 745
• Identity: 161/745 - (21%)
• Similarity: 297/745 - (39%)
• Gaps: 168/745 - (22%)

  Fly   113 SEILKS-IDVTVDPCDDFYGYSCNQW---------IKNNPIPEGKSTW-------GTFGKLE-QM 159
            :|.|:| :|....||::||.|:|..|         :::......:..:       .|.|.:: .:
  Fly    37 AEQLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTDTLGLIDHSV 101

  Fly   160 N---QLIIRNVLEKPAKSFKSDAE--RKAKVYYESCLDADEHMEKLGAKPMNDLL--------LQ 211
            |   :|::|   .:...||:||:.  .:.::||.||    :.::....|....||        ..
  Fly   102 NRKLELLLR---RRNESSFESDSSILEQMRLYYRSC----KRLKPYNLKKYLQLLPPSNSTQWPS 159

  Fly   212 IG-GWNVTKSGYNVANW--TMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPT 273
            :| ||...:     .:|  |:|...  ||.      |.|..:.|:                .||.
  Fly   160 VGRGWRPER-----FDWITTLGRLR--LHG------LNGVLLREE----------------VLPR 195

  Fly   274 AD-------YYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLE 331
            .|       |.|..:....:.:.|  ..|.::.:.:|..:..|.|....|.:||:||..    |:
  Fly   196 WDDSRNYSIYVNKPSRQETQPMGE--GAMIELLLDIGQTKRTANALARQVDDFERKLHR----LQ 254

  Fly   332 DRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDD------EVVVVYAPDFLKNLS 390
            :..::|.. ..|||..|....|.|.|....        |:|..|      ..:::....:|:.||
  Fly   255 ELEDDEGP-REMQLGYLDSYLPQLRWLSFM--------RQVRIDSELDLRSTLIIENIPYLRALS 310

  Fly   391 DIILKMEQTEEGKITLNNYLV--WQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWR-YCVS 452
            |:   ||  .|...|:.:|::  |                      .|.:...|..:|.| .||:
  Fly   311 DL---ME--SESPDTVCSYIMLKW----------------------LAFLKQQGPADISRGECVA 348

  Fly   453 DTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAI-----EKA 512
            .....:..| .:..|.|.|   |.|.:|..::.:.:..|:....:...::......:     :|.
  Fly   349 ALRRAMPLA-SSWLVGQQF---SDPESESYVSSLFQRLKVRFGQILAENRMRLSPPLVHILQQKL 409

  Fly   513 NQISDMIGFPDYILDPVE-LDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMT 576
            ..:...:||  :..:.:| :::.:..::::.::::.|.:.:....:::|...|  .:|.||:..:
  Fly   410 RAVRLQMGF--FQTEEIEDVEQYHVRIDLSGHSFYGNQLVLLRQRVEANHDLL--YINVTNFANS 470

  Fly   577 PQTVNAY-------------YTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAF 628
            ..:..:|             |...:|.::.|.|:||.|.:..|.........||.|:.|||.|.|
  Fly   471 TGSNLSYLSESWEASNSSPLYVRPRNLVLVPHGLLQLPIWHRNISALQQHAVMGFVLAHELAHGF 535

  Fly   629 DDQGREYDKFGNINRWWDSKSIER-FNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKA 692
            |..|.:||..|||....:.....| |.:..:|:.:|.:         .|.:.:.|.:||...|:.
  Fly   536 DMLGMDYDAMGNIMGPVEEIGASRQFRQGLQCLQQQMA---------TGSKWIDEKLADFVALRL 591

  Fly   693 AYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKD-PHSPSQFRVI 756
            ||..:...:..|:.....||  ..:..||||::|||.:|..|...:...|.|.. .|:..:.||:
  Fly   592 AYETFFGVRDKREPRDPLLP--QFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHLKHAADELRVM 654

  Fly   757 GTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            .||:|.:||:..|.|....:|..:::|.:|
  Fly   655 QTLANFEEFSREFGCDKKAKMQASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	155/730 (21%)
Nepl5	NP_609022.1	M13	48..682	CDD:341056	155/730 (21%)