Protein Alignment Nep3 and Phex

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_037136.2
• Gene: Phex / 25512
• RGDID: 3323
• Length: 749
• Species: Rattus norvegicus
• Alignment Length: 756
• Identity: 258/756 - (34%)
• Similarity: 414/756 - (54%)
• Gaps: 50/756 - (6%)

  Fly    54 LLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKS 118
            :.:..|:....:...|:.|.:.|        :|..|..|:        .||...||.|::.|:..
  Rat    21 IALALFITGTLVLGTLLFLVSQG--------LLSFQAKQE--------YCLKPECIEAAAAIMSK 69

  Fly   119 IDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKP-AKSFKSDAERK 182
            ::::||||::|:.::|:.||.||||||...::|.:..|.....|.::.:|||. ::...::|.:|
  Rat    70 VNLSVDPCENFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKALLEKSVSRRRDTEAVQK 134

  Fly   183 AKVYYESCLDADEHMEKLGAKPMNDLLLQIG-GWNVTKSG------YNVANWTMGHTLKILHNKY 240
            ||:.|.||:: ::.:||..|||:..:|.... .|.|.::.      ::...:::..||.....:|
  Rat   135 AKILYSSCMN-EKAIEKADAKPLLHILRHSPFRWPVLEANIGPEGVWSERKFSLLQTLATFRGQY 198

  Fly   241 NFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPT-ADYYNNKTD--NHRKVLNEYIEYMTKVCVLL 302
            :.:......:..|||.|:.|::::||..|:|.. .|:.:|.|:  ::|..|   .::|....|||
  Rat   199 SNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDFLDNTTEAKSYRDAL---YKFMVDTAVLL 260

  Fly   303 GANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDH----FDN 363
            |||.|.|...|..|:..|.|:|.|.||.|: |..||||:.|.:.:||.:.|..:|..:    .|.
  Rat   261 GANSSRAEHDMKSVLRLEIKIAEIMIPHEN-RTSEAMYNKMNISELSAMIPQFDWLGYIKKVIDT 324

  Fly   364 AMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRD 428
            .:....:.:...|.|||..|.:.|:|..|:     ..|.|.|:.|||||:.|.:....||:.|:.
  Rat   325 RLYPHLKDIGPSENVVVRVPQYFKDLFRIL-----GAERKKTIANYLVWRMVYSRIPNLSRRFQY 384

  Fly   429 AYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAF--K 491
            .:....:.:.|:......|..||:...:.:.:.||.:||...|..:.|...|::|..:|.||  .
  Rat   385 RWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVNVHFQEDKKEMMEELIEGVRWAFIDM 449

  Fly   492 MNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYN 556
            :..:| .|:|..|:.||.|||..:...:|:|::|::...:::....:..:.:.||.|.:|...|.
  Rat   450 LEKEN-EWMDAGTKRKAQEKARAVLAKVGYPEFIMNDTYVNEDLKAIKFSESDYFGNVLQTRKYL 513

  Fly   557 LKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFF-DINNPKSLNFGAMGVVM 620
            .:|:...|.:.|.||.|...|.||||:|:.:.|||.||||.||.||| ....|:||::||:||::
  Rat   514 AQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIV 578

  Fly   621 GHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY--KMNGRTLNGKQTLGEN 683
            |||.||.||:.||:|||.||::.||...|.|:|.||::|:..|||.|  |..|..:.||:|||||
  Rat   579 GHEFTHGFDNNGRKYDKNGNLDPWWSVDSEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGEN 643

  Fly   684 IADNGGLKAAYHAYQRTKSDR--DVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKD 746
            |||||||:.|:.||::..:||  .|:...|||:..|::||||:|:|.|.|:|...|....|::..
  Rat   644 IADNGGLREAFRAYRKWINDRRQGVEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIG 708

  Fly   747 PHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMN-PTEKCEVW 786
            .|||.||||.|.:||.:||.:.|.|.....|| ..:.|.:|
  Rat   709 AHSPPQFRVNGAISNFEEFQKAFNCPANSTMNRGADSCRLW 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	243/683 (36%)
Phex	NP_037136.2	M13	74..740	CDD:341056	241/676 (36%)