Protein Alignment Nep3 and Kel

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_115929.3
• Gene: Kel / 23925
• MGIID: 1346053
• Length: 713
• Species: Mus musculus
• Alignment Length: 773
• Identity: 211/773 - (27%)
• Similarity: 369/773 - (47%)
• Gaps: 98/773 - (12%)

  Fly    39 RATWNWRSRNKTEKWLLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPC 103
            |....|..:....:|:|     :|:.:..||:      |||....::.      ::|   ...||
Mouse    14 RLPTEWSRQLTRARWVL-----LAVLLCGLLL------GSSMLWFYIF------RNC---GPCPC 58

  Fly   104 LNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVL 168
            ....|:......|.|.:.:|.||.||:.::|.         :...|..:|..|.:.|:..:..:|
Mouse    59 ETPVCMELLDHYLASGNRSVAPCTDFFSFACE---------KANGTSDSFQALTEENKSRLWRLL 114

  Fly   169 EKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWT---MG 230
            |.|........|.||..:|.||:|.|. :|..|:.|:..::.::||||:|      .|||   ..
Mouse   115 EAPGSWHLGSGEEKAFQFYNSCMDTDA-IEASGSGPLIQIIEELGGWNIT------GNWTSLDFN 172

  Fly   231 HTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYM 295
            ..|::|.::|.....|...:..........:|||||....:........|.  :.::|.||:.|:
Mouse   173 QNLRLLMSQYGHFPFFRAYLRPHPAPPHTPIIQIDQPEFDILLQQEQEQKV--YAQILREYVTYL 235

  Fly   296 TKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDH 360
            .::..|||:|..:|:......|.|..:|.....|.:.::.::.::|.:.:.:|.::||.::|.
Mouse   236 NRLGTLLGSNPQEAQQHASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVTIDELQEMAPAIDWL-- 298

  Fly   361 FDNAMQMV--GRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKI----TLNNYLVWQAVRTLT 419
              :.:|.:  ...:...:.:||:..|:|:|:|.::      |||.:    ::.:|::...|.||:
Mouse   299 --SCLQAIFTPMSLNSSQTLVVHDLDYLRNMSQLV------EEGLLNHRESIQSYMILGLVDTLS 355

  Fly   420 SCLSKPFRDAYKGVRKALMGSDGGEEI--------------WRYCVSDTNNVVGFAVGAIFVRQA 470
            ..|...|::|    |:.|:     :|:              |..||..|.......:.|:|||:|
Mouse   356 PALDTKFQEA----RRELI-----QELRKLKERPPLPAYPRWMKCVEQTGAFFEPTLAALFVREA 411

  Fly   471 FHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKY 535
            |....:.||.::.|||::|..:.|:.|:|:.::|:::|:.|..|:...:|.|...:.|....::|
Mouse   412 FGPSIQSAAMELFAEIKDAVIIRLKKLSWISEETQKEALNKLAQLQVEMGAPKRAVKPDIATQEY 476

  Fly   536 AELNITPNAYFENNIQVAIYNLKS-NLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQ 599
            .::.:.|:  |..:....:.:|:: |::...||.....|..:|..|||||:.:.:.:|||||:||
Mouse   477 NDIQLGPS--FLQSFLSCVRSLRARNVQSFLQPFPYHRWQKSPWEVNAYYSISDHMVVFPAGLLQ 539

  Fly   600 TPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQY 664
            .|||....|:::||||.|.:|.|||.|.|      |...  :.....:.......|...|:.|.|
Mouse   540 PPFFHPGYPRAVNFGAAGSIMAHELLHIF------YQLL--LPGGCPACDTHVLQEALLCLERHY 596

  Fly   665 SGYKMNG-RTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQ 728
            :.:.:.. .:.||..||.||.||.||:..|:.||.:...:...: |.||.|:|:..||||.|:||
Mouse   597 AAFPLPSISSFNGSHTLLENAADIGGVAIAFQAYSKRIVEHTGE-LTLPNLDLSPYQLFFRSYAQ 660

  Fly   729 VWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            |.|...:.     |..:|||||...||.|.|||..:||:.|.|..|..:||:.:|::|
Mouse   661 VMCRGLSS-----QDPQDPHSPPSLRVHGPLSNTPDFAKHFHCPRGTLLNPSARCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	193/685 (28%)
Kel	NP_115929.3	M13	78..711	CDD:341056	193/685 (28%)