Protein Alignment Nep3 and nep-24

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 642
• Identity: 127/642 - (19%)
• Similarity: 240/642 - (37%)
• Gaps: 141/642 - (21%)

  Fly    66 FTLLIVL-----FTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDP 125
            |.||::|     ...|.::.||::|                 |....||..:..:....|.:|||
 Worm    13 FMLLLLLTCTAPLAIGATTPATRNV-----------------CNTPACITLAHMLHNYHDPSVDP 60

  Fly   126 CDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESC 190
            ||:|:.::|.:       .....|...:.|..:....|::..|:|...| :|.:|...:..|::|
 Worm    61 CDNFHQFACGR-------EHEHETEDIYTKKTKTINNIMKRFLKKNETS-RSKSENAMRTLYKAC 117

  Fly   191 LDADEHMEKLGAKPMNDL---LLQIGGWNVTKSGYNVANWTMGHTL--KILHNKYNFNCLF---- 246
            ...:::......|.:.|:   :..||.|.|....::.:.:.:...|  .:...:.||. ||
 Worm   118 KTLEKNSTASRNKALQDIFQDIQSIGAWPVVDDKWDESKFDLNDFLVNLVRLGRKNFG-LFQMAR 181

  Fly   247 -----GWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMT--------KV 298
                 .:|||.:  .:.||.:.:   |.|:......|:...|::|:|::..||:.        |.
 Worm   182 YVNVRNFAIGPE--AAWRHNVDL---GKTISEILKANSVQTNNKKLLDDLAEYVNLEKALSQHKF 241

  Fly   299 CVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDN 363
            ..:........|:..:..:||.:.:..:..|  |:|.               |.|.:....:..|
 Worm   242 NTVQPGYIFSERSDFVSSVNFSRLVLEMMSP--DKRT---------------LFPEVYQIMYLTN 289

  Fly   364 AMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRD 428
            .....|:.               .||..||     ....|..|.|||:::.:.|..:.|:
 Worm   290 TSLFFGKN---------------NNLETII-----RNTSKRALANYLIFKFIDTSIADLT----- 329

  Fly   429 AYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMN 493
                     .||...     :|.....|.:..|....|.|.....|::    :.|.::.||.::.
 Worm   330 ---------YGSPSA-----FCEQKVINFLPRAALRAFYRNFISKENR----KKITKLTEATQVQ 376

  Fly   494 LQNL----TWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAI 554
            |..:    .|:..::::.|:::.:.::.:||:|||...|.:||..:..||::.:..:
 Worm   377 LLKIIGATDWMSIKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGLFEHLNLSSSDTY-------- 433

  Fly   555 YNLKSNLKRL--DQPVNKTNWGMTPQ-------TVNAYYTPTKNQIVFPAGILQTPFFDINNPKS 610
            |.:...:.|.  :|.::... |..|.       ..||.|....|.::..|.....||||.:.|..
 Worm   434 YTVVRKINRFMREQEMDYYT-GEVPYYPLFPGLMTNAMYNANDNNLMIFAPFFDDPFFDSSFPDY 497

  Fly   611 LNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY 667
            .|.......:.||:.|.|.....:. ..|....|...|..|.:.::.:|:..||:.|
 Worm   498 ANIAFTSNTLAHEMGHTFSPHLMDI-MTGTTEVWLTPKETEEYEKRVKCLEDQYTEY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	115/580 (20%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:472708	115/580 (20%)