Protein Alignment Nep3 and nep-2

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_494343.2
• Gene: nep-2 / 188090
• WormBaseID: WBGene00020230
• Length: 736
• Species: Caenorhabditis elegans
• Alignment Length: 762
• Identity: 261/762 - (34%)
• Similarity: 415/762 - (54%)
• Gaps: 56/762 - (7%)

  Fly    46 SRNKTEKWLLITTFVMAITIFTLLIVLFTDGGSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIF 110
            :::...:|..|...:..|.:...|:||    |::      ::...:.||...    .||:..||.
 Worm    10 TKSPGSRWTRIWAIIALILLILFLLVL----GAA------IYFYINYKDSSD----VCLSPGCIK 60

  Fly   111 ASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAK-- 173
            .:|.||.|::.:||||||||.::|.||||.:|||:...:...|..|.|..:..::.:|::..:
 Worm    61 TASVILSSMNSSVDPCDDFYEFACGQWIKGHPIPDDAPSVSNFENLGQDLEFALKELLDENDEPY 125

  Fly   174 SFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLK---- 234
            .:::.|..|||.:|..||:..|.::. .....::::...|||.           ::||.:|
 Worm   126 DYETSAVGKAKYFYNLCLNESEILDN-WRTTFDEVVKSFGGWP-----------SLGHQMKPDAS 178

  Fly   235 --ILH----NKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIE 293
              :|:    .|:..:.||...:..|||||.|||:.|||..|.|...|:|....:..|..   |::
 Worm   179 IEMLYADMVAKFKADSLFKATVQPDDKNSQRHVLLIDQPQLNLFARDFYVAAENEERMA---YLQ 240

  Fly   294 YMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWT 358
            .:..|.:||.|:.:.|......:|:||..|||||:..|.|.:...:|..:.|.::.:..|..||.
 Worm   241 LIRDVLILLDADRTRATLDAKEIIDFETALANITMADEHRHDIAELYTKITLGEMRRSLPHFNWP 305

  Fly   359 DHFDNAMQMV----GRRVT--DDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVW-QAVR 416
            ..|:...:.:    |:|:|  |:..||||..:||:.|..:|.:.:..     .:.|||.| ...:
 Worm   306 LFFNRMFKDLHEKNGKRITFDDNTEVVVYGYEFLRRLDVLIPQYDNR-----LIVNYLEWCWFFK 365

  Fly   417 TLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQ 481
            |:...|..||........|.|...:..:..|..||:..|:::..|..||:|:..|..|:|...|:
 Worm   366 TMLRDLPDPFALTIFKFYKTLNIMNVQKVRWHGCVTRINSLMPMATSAIYVKNHFDHEAKQQVEE 430

  Fly   482 MIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYF 546
            ||:.|.|:|...|.:..|:.|:|::.|.:|.|::...||:|||:.||..::.:|....:.|..|:
 Worm   431 MISLIMESFVDLLLSEDWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYY 495

  Fly   547 ENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSL 611
            :..........:..|:|:.:.|::..|......|||:|:|..|:|:|||||||..|:..:.|.|:
 Worm   496 QTKFSFYEQYQRDVLERITEAVDRERWVAGAALVNAFYSPNTNEIIFPAGILQPVFYSKDFPSSM 560

  Fly   612 NFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMN--GRTL 674
            |||.:|||:|||:||.|||:||.||..|||.:|||:.:|.:|..|::||.:|||.|.::  ...:
 Worm   561 NFGGIGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHKAQCIEKQYSSYVLDQINMQI 625

  Fly   675 NGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETN 739
            |||.|.|||||||||||.||.||::.:. |.....:|||:||||.||||:::||:||.:..|:..
 Worm   626 NGKSTKGENIADNGGLKQAYRAYKKYEK-RHSRPPRLPGVNLTHDQLFFLNYAQIWCGTMNDKEA 689

  Fly   740 LLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            :.::....|||...||.|.|||..:||:.:.|:||.:|||.|||.||
 Worm   690 IRKLRTSEHSPGPIRVKGPLSNSYDFAKAYNCEPGSQMNPREKCRVW 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	241/681 (35%)
nep-2	NP_494343.2	M13	73..734	CDD:341056	241/681 (35%)