Protein Alignment Nep3 and nep-8

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_001309548.1
• Gene: nep-8 / 184631
• WormBaseID: WBGene00017553
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 748
• Identity: 160/748 - (21%)
• Similarity: 313/748 - (41%)
• Gaps: 142/748 - (18%)

  Fly    63 ITIFTLLIVLFTDGGSSDATKHVLHVQPHQKD--CPSGNELP----CLNKHCIFASSEILKSIDV 121
            :.:..||:::|.    :..|.|: .|:|...|  ...||::.    |.:..||..|.|:|...|.
 Worm    15 VAVNLLLLIVFL----AMVTVHI-KVEPVNLDELLSIGNDVDSKNLCDSPECITLSHELLNYQDP 74

  Fly   122 TVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLI---IRNVLEKPAKSFKSDAERKA 183
            :||||.||:.:||.::.:.: :.|        .:|::...::   ||..|.|...| .|.:|...
 Worm    75 SVDPCVDFFQHSCGRFHEQS-VSE--------SRLQKKKHILRKQIREFLHKIQNS-TSKSENLM 129

  Fly   184 KVYYESCLDADEHME----KLGAKPMNDL---LLQIGGWNVTKSGYNVANWTMGHTLKILHNKYN 241
            |:.::.| :|.:...    |:....::|:   :.:||.|.:...     ||.        .:|::
 Worm   130 KLVFDKC-EASKKTSNDNYKISRDAIHDVFNDIKKIGAWPLLDK-----NWD--------GSKFD 180

  Fly   242 FNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANE 306
            .|.:..            :::::....|.|...|:         ::|.|  ....::...||:..
 Worm   181 LNEMLS------------NLVKLGATNLGLFQLDF---------RILTE--GKFVRIAPTLGSIV 222

  Fly   307 SDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPF---------------LN 356
            .:  :.||.:|:...:...:....|:...|...|..:|:    |||.:               :|
 Worm   223 HN--STMISMISEILEANGVQPDSEEISKEFEEYSSLQM----KLAKYQSSGKLSISLPGVRSIN 281

  Fly   357 WTD------HFDNAMQMVGR-RVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQA 414
            ::.      |.....::.|: ||...|..:.:..:..::|..||   |.|...  ||.|:|::..
 Worm   282 FSSLITEMIHPSRVSKIFGKIRVVTSEHPLFFKSNETESLDTII---ESTSNK--TLANFLIFNY 341

  Fly   415 VRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAA 479
            :::..:.:        ||.|:.            .|..|.......|...:|:|......::...
 Worm   342 IQSSYNIM--------KGARRG------------NCEDDVRREFPRASLRVFMRNFVDKGNRDGV 386

  Fly   480 EQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNI-TPN 543
            :::..|:::.....:|:...:....:|..::|...|...||:||:...|..|||::...:: :.:
 Worm   387 KKLTEELKKNTLEMIQDTENLAPPVKESMLKKVEAIKVTIGYPDHFDPPGTLDKEFENFDLDSTD 451

  Fly   544 AYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQT-------VNAYYTPTKNQIVFPAGILQTP 601
            :|:.      |:. |.|..|.:|.:.... |.||.:       |||.|..:||.:...|..|..|
 Worm   452 SYYR------IFQ-KLNRLRSEQQMEFIA-GETPISPIKEVLKVNANYKRSKNALTVFAPFLDDP 508

  Fly   602 FFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSG 666
            ||||..|..:|....|.::.||:.|:.|..|..||:.|........:.:..:.::.:|:..||..
 Worm   509 FFDITYPDYVNLFFSGFLIAHEIGHSVDANGLGYDENGKPMDGIRLEHVTEYGKQGQCLVDQYDN 573

  Fly   667 Y--KMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQV 729
            |  .:.|:.:||..::.|.|||..|.:..:.||::..:.:.:.::.|..:|:  .||:|...:.:
 Worm   574 YDDPVYGKKMNGTHSINEIIADWVGHEVTWRAYKKMDTSKMLSLIGLKDINM--DQLYFRVQSLL 636

  Fly   730 WCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNM 762
            :|.. .|..:|.:..||.:....|||.|..:.:
 Worm   637 FCRE-RDTISLEETLKDVYPTDNFRVNGAYARV 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	143/682 (21%)
nep-8	NP_001309548.1	M13	76..664	CDD:341056	142/676 (21%)