Protein Alignment Nep3 and nep-17

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_001254395.1
• Gene: nep-17 / 174996
• WormBaseID: WBGene00010070
• Length: 1589
• Species: Caenorhabditis elegans
• Alignment Length: 819
• Identity: 223/819 - (27%)
• Similarity: 342/819 - (41%)
• Gaps: 179/819 - (21%)

  Fly    94 DCPSGNELPCLNKHCIFASSEI---------------------------------------LKSI 119
            :|||....|  :.||....|:|                                       .||:
 Worm   818 NCPSSTYAP--DNHCNVWVSDIDTTFGLPNVKTDINVVPEAPITSTNVDKMNAYQMAVDYYAKSV 880

  Fly   120 DVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSF---KSDAER 181
            :..:|||||||.|:|..:  |..:        :|......|.:.:...||.|....   .|.|.:
 Worm   881 NTAIDPCDDFYSYACGNF--NQSV--------SFYTARAQNLVYMAQKLEDPTYQTTINSSPALK 935

  Fly   182 KAKVYYESCLDA---------------------DEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVA 225
            |.|..|.:||.|                     |:....:|    .|..|..||.....|...:
 Worm   936 KEKQLYNACLTATASSQSEDQILISKNYIQTKVDDLKTLIG----QDFTLVNGGAPKLPSAKQI- 995

  Fly   226 NWTMGHTLKILHNKYNFNCLFG------WAIGEDDKNSSRHVIQIDQGGLTLPTADYYN------ 278
                |..|..|..:...:.|..      |.     .||..:.:.|||....| :..||.
 Worm   996 ----GDALGYLSFEQGIDTLISPLVDTYWI-----DNSKGYQMFIDQNTAYL-SKTYYQPAAWKI 1050

  Fly   279 NKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLED--RRNEEAMYH 341
            .|....:..|:....|..:..:.|.|..||.   :..|:::|:.:| :....:|  ||..:..::
 Worm  1051 EKPKYLKMALDVVTRYAREQNITLPAGASDL---LSNVLDYEQNIA-VKYSTDDNTRRQFQRSWN 1111

  Fly   342 PMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDD--EVVVV-------YAPDFLKNLSDIILKME 397
            ..:...|.....|::|..:..:|...|..::||.  :|.|:       ::.|:|:...::::.:.
 Worm  1112 LTKTSDLVTKYNFMDWMTYLSHAPNAVKAKITDANYQVSVMEVDRLTHFSADYLQQSPELLVNLL 1176

  Fly   398 QTEEGKITLNN--YLVWQAVRTLTSCLSKPFRDAYKGV--RKALMGSDGGEEIWRY--------- 449
            ..   ::.|.|  |:             ..:..|::|:  ....:|....:.|..:
 Worm  1177 FV---RLLLGNAQYI-------------PSYASAFRGMTDESIFLGLSRRKTIPNHIPPPNFDLE 1225

  Fly   450 -----CVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQ----------MIAEIREAFKMNLQNLTW 499
                 |.|..||::.||.|.:||...:     |.|:.          :|..:..:|:..:..|.|
 Worm  1226 ANGPACASVANNLMQFANGRVFVDYMY-----PTAQDVTNIRKSAGGIIKNVISSFQGMIDQLDW 1285

  Fly   500 VDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAI-YNLKSNLKR 563
            :...|::||..|..||...|.|||:|.:...|...|:.|.|..:..|.:.....| :|:.....:
 Worm  1286 MAPDTKQKAYAKTVQIQQNIAFPDWIKNDTLLGNYYSTLVIADSDNFYDIYDKLIKFNIFVQYNQ 1350

  Fly   564 LD-QPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHA 627
            |: ...::|::...|.||||:|.|..|.|.||||||..|:|:.|.|.|:|:|.||:|.||||||.
 Worm  1351 LNAAQTDRTDFLGQPGTVNAWYQPELNSITFPAGILVPPYFNPNWPPSINYGGMGLVAGHELTHG 1415

  Fly   628 FDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGY------KMNGRTLNGKQTLGENIAD 686
            |||||.::...||:.||.|..|:..|...|:|:..:|||:      ..:...:.|.||.||||||
 Worm  1416 FDDQGVQWGPTGNLARWMDDNSMAGFKNMSQCVINEYSGFCPLNATNYSPNCVKGPQTQGENIAD 1480

  Fly   687 NGGLKAAYHAYQRTKSDRDVDILKLPGL---NLTHSQLFFVSFAQVWCS-STTDETNLLQMEKDP 747
            |||:.||::|| :|....|....:||..   ..||.||||:|||||||. ..||:....|:..||
 Worm  1481 NGGVHAAFNAY-KTHQSLDGPDPRLPDRLFGQFTHDQLFFMSFAQVWCEVRRTDDALYTQIMVDP 1544

  Fly   748 HSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            ||||.:||.||:.|...|...|.|..|.:..|.:.||||
 Worm  1545 HSPSMYRVYGTIQNFPAFQTAFNCPLGSKSAPEQHCEVW 1583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	209/747 (28%)
nep-17	NP_001254395.1	M13	112..831	CDD:341056	5/14 (36%)
		M13	884..1581	CDD:341056	209/747 (28%)