Protein Alignment Nep3 and nep-1

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_496490.2
• Gene: nep-1 / 174787
• WormBaseID: WBGene00013926
• Length: 754
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 242/713 - (33%)
• Similarity: 383/713 - (53%)
• Gaps: 67/713 - (9%)

  Fly   111 ASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGK-----LEQMNQLIIRNVLEK 170
            ||..:.||:::::||||||:.|:|..|:.::|||:..:::..|..     |.:|.:|...|....
 Worm    72 ASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIP 136

  Fly   171 PAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHT--- 232
            .:||.     ...|..|.:|:|.::| ..:||:   |||.:|..:     ||    |.|.|.
 Worm   137 TSKSI-----ALIKQIYNTCMDTEKH-NAVGAR---DLLEKIKTY-----GY----WPMVHNEKW 183

  Fly   233 -------LKILHN---KYNFNCLFGWAIGEDDKNSSRHVIQIDQG--GLTLPTADYY--NNKTDN 283
                   .|:|.|   ..:.:..|.:...||.:|.||.::..|||  ||...|.|||  ..|.:.
 Worm   184 RESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEK 248

  Fly   284 HRKVLNEY----IEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQ 344
            ..|...:|    :.|.|:... :..|||...:.:..:|.|||:.|.|.:..|||||...:|:..:
 Worm   249 QMKAYRKYTIGKVRYYTEDAG-MAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRR 312

  Fly   345 LRQLSKLAPFLNW------TDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGK 403
            ...|.:....::|      |..|     :|...:..:..:::...::|:.::.::    |..:.:
 Worm   313 FDDLKEYMSIIDWKKLTLSTTPF-----LVHSYLKTNPSIIISDVEYLQKMNTLL----QNTDPR 368

  Fly   404 ITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVR 468
            | :.||::.:...:.:..:.|.:.|..:.....:.|....:..|:.|||.....:.:|.|:::||
 Worm   369 I-VTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVR 432

  Fly   469 QAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDK 533
            :.|...:|.....||.:::|||:..:....|:|.:|::.|:|||:|:...||:||:||:..:||.
 Worm   433 KYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDD 497

  Fly   534 KYAELNITPNAYFENNIQVAIYNLKSNL--KRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAG 596
            .|..|...|...|...::.:| ..::|.  :||.:|||:..:..:...|||:|:||:|.|.||||
 Worm   498 WYKGLEGAPEDSFSQLVEKSI-QWRNNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAG 561

  Fly   597 ILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIA 661
            |||.||||...||:||:|.:|.|:|||:||.|||.||::|..||:..|||:.:..:|||:::||.
 Worm   562 ILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCII 626

  Fly   662 RQYSGYKMNGRTL--NGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGL-NLTHSQLFF 723
            .||:..|:.|..|  |||.|.|||||||||:|.|:.||:...........:||.. :||:.||||
 Worm   627 EQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFF 691

  Fly   724 VSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            |.:|||||.:.|.||..|.:..|||||...||...|:|..||||.|:|..|..||||::|.||
 Worm   692 VGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	235/697 (34%)
nep-1	NP_496490.2	M13	85..751	CDD:341056	235/695 (34%)