Protein Alignment Nep3 and Mme

DIOPT Version :10

• Sequence 1: NP_523417.2
• Gene: Nep3 / 33005
• FlyBaseID: FBgn0031081
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_032630.2
• Gene: Mme / 17380
• MGIID: 97004
• Length: 750
• Species: Mus musculus
• Alignment Length: 764
• Identity: 278/764 - (36%)
• Similarity: 424/764 - (55%)
• Gaps: 59/764 - (7%)

  Fly    49 KTEKW----LLITTFVMAITIFTL-LIVLFT--DGGSSDATKHVLHVQPHQKDCPSGNELPCLNK 106
            |.::|    :.::..|:.:||..: :|.|:.  |.|.                        |.:.
Mouse    20 KKQRWTPLEISLSVLVLLLTIIAVTMIALYATYDDGI------------------------CKSS 60

  Fly   107 HCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKP 171
            .||.:::.:::::|.:|:||.||:.|:|..|:|.|.|||..|.:..|..|....::|:::||::|
Mouse    61 DCIKSAARLIQNMDASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQEP 125

  Fly   172 AKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNV---ANWTMGHTL 233
             |:....|.:|||..|.||:: :..::..|.:|:..||..|.||.|....::.   .:||...::
Mouse   126 -KTEDIVAVQKAKTLYRSCIN-ESAIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSI 188

  Fly   234 KILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKV 298
            ..|::||....|..:.:|.|||||::|:|..||..|.||:.||| ..|..:::....|:::|..|
Mouse   189 AQLNSKYGKKVLINFFVGTDDKNSTQHIIHFDQPRLGLPSRDYY-ECTGIYKEACTAYVDFMISV 252

  Fly   299 CVL------LGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSK------L 351
            ..|      |..:|:....:|..|:..||::||.|...|||.:...:|:.|.|.:|..      .
Mouse   253 ARLIRQEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEVN 317

  Fly   352 APFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVR 416
            ....:|::..:..|..|...:.::|.||||||::|..|..|:.|....:     |.|.:.|:.:.
Mouse   318 GKSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRD-----LQNLMSWRFIM 377

  Fly   417 TLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQ 481
            .|.|.||:.::::....||||.|:......||.|.:..|..:..|||.::|..||.||||...|.
Mouse   378 DLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVED 442

  Fly   482 MIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYIL-DPVELDKKYAELNITPNAY 545
            :||:|||.|...|.:|||:|.:|::||.|||..|.:.||:||.|: :..:|:.:|.|||...:.|
Mouse   443 LIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEY 507

  Fly   546 FENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKS 610
            |||.||...::....||:|.:.|:|..|......|||:|:..:|||||||||||.|||......|
Mouse   508 FENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNS 572

  Fly   611 LNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMN---GR 672
            ||:|.:|:|:|||:||.|||.||.::|.|::..||..:|...|.::|:|:..||..:..:   |:
Mouse   573 LNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQ 637

  Fly   673 TLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDE 737
            .|||..|||||||||||:..||.|||........:.| ||||:|.|.||||::||||||.:...|
Mouse   638 HLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKL-LPGLDLNHKQLFFLNFAQVWCGTYRPE 701

  Fly   738 TNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786
            ..:..::.|.|||..||:||||.|..|||:.|.|:....|||..||.||
Mouse   702 YAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nep3	NP_523417.2	M13	123..784	CDD:341056	262/679 (39%)
Mme	NP_032630.2	Stop-transfer sequence. /evidence=ECO:0000255	16..23		1/2 (50%)
		M13	77..748	CDD:341056	262/679 (39%)